Molecular structure of DL-Goitrin, CAS Number: 13190-34-6
DL-Goitrin (CAS 13190-34-6)
See product citations (6)
Alternate Names:
( -)-Goitrin; 5-Vinyloxazolidone-2-thione
Application:
DL-Goitrin is a sulfur-containing oxazolidine, a cyclic thiocarbamate, that reduces the production of thyroid hormones such as thyroxine
CAS Number:
13190-34-6
Purity:
≥98%
Molecular Weight:
129.18
Molecular Formula:
C5H7NOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
DL-Goitrin is a naturally occurring compound abundant in various plants, such as cabbage, kale, and mustard. In vitro studies utilize cell cultures and laboratory techniques to investigate the compound′s effects. The precise mechanism of action of DL-Goitrin remains partially elusive. However, it is hypothesized that DL-Goitrin may impede the activity of specific enzymes responsible for thyroid hormone synthesis. Moreover, DL-Goitrin may also inhibit certain proteins involved in the regulation of thyroid hormones. These properties make DL-Goitrin an intriguing subject of scientific research in the field of thyroid biology and hormone regulation.
DL-Goitrin (CAS 13190-34-6) References
- Germination stimulants of Phelipanche ramosa in the rhizosphere of Brassica napus are derived from the glucosinolate pathway. | Auger, B., et al. 2012. Mol Plant Microbe Interact. 25: 993-1004. PMID: 22414435
- Glutathione S-transferase subunit induction patterns of Brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: a new approach for the identification of inducing xenobiotics. | Bogaards, JJ., et al. 1990. Food Chem Toxicol. 28: 81-8. PMID: 2341092
- Determination of goitrogenic metabolites in the serum of male wistar rat fed structurally different glucosinolates. | Choi, EJ., et al. 2014. Toxicol Res. 30: 109-16. PMID: 25071920
- In vitro metabolic conversion of the organic breakdown products of glucosinolate to goitrogenic thiocyanate anion. | Lee, J. and Kwon, H. 2015. J Sci Food Agric. 95: 2244-51. PMID: 25271103
- Revealing the Macromolecular Targets of Fragment-Like Natural Products. | Rodrigues, T., et al. 2015. Angew Chem Int Ed Engl. 54: 10516-20. PMID: 26202212
- Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries. | Paul Friedman, K., et al. 2016. Toxicol Sci. 151: 160-80. PMID: 26884060
- Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes. | Tran, HTT., et al. 2018. Front Immunol. 9: 2949. PMID: 30619309
- Qing-Kai-Ling Injection Induces Immediate Hypersensitivity Reaction via the Activation of Anaphylatoxin C3. | Gao, Y., et al. 2019. Front Pharmacol. 10: 1524. PMID: 31998128
- Effects of Plant Hormones, Metal Ions, Salinity, Sugar, and Chemicals Pollution on Glucosinolate Biosynthesis in Cruciferous Plant. | Liu, Z., et al. 2022. Front Plant Sci. 13: 856442. PMID: 35574082
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DL-Goitrin, 100 mg | sc-268967 | 100 mg | $468.00 |