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DL-Glyceraldehyde 3-phosphate solution (CAS 591-59-3 (free acid))

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Datasheets
Alternate Names:
3-phosphoglyceraldehyde solution
CAS Number:
591-59-3 (free acid)
Molecular Weight:
170.06
Molecular Formula:
C3H7O6P
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Glyceraldehyde 3-phosphate solution, a phosphorylated derivative of glyceraldehyde, serves as a crucial intermediate in glycolysis, the metabolic pathway responsible for the conversion of glucose into pyruvate. In research, this compound is utilized to investigate the enzymatic steps of glycolysis and its regulation in various biological systems. DL-Glyceraldehyde 3-phosphate is generated during the cleavage of fructose-1,6-bisphosphate by the enzyme aldolase, leading to the formation of two triose phosphates, including glyceraldehyde 3-phosphate. Subsequently, glyceraldehyde 3-phosphate undergoes further enzymatic reactions, ultimately yielding pyruvate, ATP, and NADH, which are essential for cellular energy production. Researchers often employ DL-Glyceraldehyde 3-phosphate solution in enzymatic assays to study the kinetics and regulation of glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase, which catalyzes the conversion of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate coupled with the reduction of NAD+ to NADH. Moreover, DL-Glyceraldehyde 3-phosphate solution is utilized in studies investigating the metabolic flux through glycolysis and its implications in cellular physiology and pathology, including cancer metabolism and metabolic diseases. Through its pivotal role in glycolysis and its applications in metabolic research, DL-Glyceraldehyde 3-phosphate solution continues to be an invaluable tool for elucidating the fundamental principles of cellular metabolism and energy production.


DL-Glyceraldehyde 3-phosphate solution (CAS 591-59-3 (free acid)) References

  1. The uncatalyzed rates of enolization of dihydroxyacetone phoshate and of glyceraldehyde 3-phosphate in neutral aqueous solution. The quantitative assessment of the effectiveness of an enzyme catalyst.  |  Hall, A. and Knowles, JR. 1975. Biochemistry. 14: 4348-53. PMID: 1182103
  2. Heterogeneity of glyceraldehyde-3-phosphate dehydrogenase from human brain.  |  Ryzlak, MT. and Pietruszko, R. 1988. Biochim Biophys Acta. 954: 309-24. PMID: 3370218
  3. Aspects of the chemistry of D-glyceraldehyde 3-phosphate dehydrogenase.  |  Trentham, DR. 1968. Biochem J. 109: 603-12. PMID: 4300829

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Glyceraldehyde 3-phosphate solution, 25 mg

sc-507252
25 mg
$221.00