Date published: 2026-5-28

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DL-AP5 Sodium salt (CAS 1303993-72-7)

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Alternate Names:
2-Amino-5-phosphovaleric acid Sodium Salt
Application:
DL-AP5 Sodium salt is a potent NMDA antagonist
CAS Number:
1303993-72-7
Molecular Weight:
219.11
Molecular Formula:
C5H11NO5P•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-AP5 Sodium salt is a sodium salt of DL-AP5, and a potent NMDA antagonist. It is used as a building block in numerous biochemical processes. This compound serves as an important component in the synthesis of proteins and various other small molecules, rendering it highly valued in the realm of biochemistry and molecular biology laboratories. In the context of protein synthesis, it acts as a substrate, facilitating the formation of peptide bonds among amino acids. Conversely, in the realm of enzyme inhibition, DL-AP5 Sodium salt binds to the active site of the enzyme, impeding its catalytic function.


DL-AP5 Sodium salt (CAS 1303993-72-7) References

  1. Functional properties of ES cell-derived neurons engrafted into the hippocampus of adult normal and chronically epileptic rats.  |  Rüschenschmidt, C., et al. 2005. Epilepsia. 46 Suppl 5: 174-83. PMID: 15987274
  2. Experimentally constrained CA1 fast-firing parvalbumin-positive interneuron network models exhibit sharp transitions into coherent high frequency rhythms.  |  Ferguson, KA., et al. 2013. Front Comput Neurosci. 7: 144. PMID: 24155715
  3. Simple, biologically-constrained CA1 pyramidal cell models using an intact, whole hippocampus context.  |  Ferguson, KA., et al. 2014. F1000Res. 3: 104. PMID: 25383182
  4. Modulation of GABA release from the thalamic reticular nucleus by cocaine and caffeine: role of serotonin receptors.  |  Goitia, B., et al. 2016. J Neurochem. 136: 526-35. PMID: 26484945
  5. Leptin alters somatosensory thalamic networks by decreasing gaba release from reticular thalamic nucleus and action potential frequency at ventrobasal neurons.  |  Perissinotti, PP., et al. 2018. Brain Struct Funct. 223: 2499-2514. PMID: 29520482
  6. TrkB-dependent disinhibition of the nucleus accumbens is enhanced by ethanol.  |  Patton, MH., et al. 2019. Neuropsychopharmacology. 44: 1114-1122. PMID: 30758322
  7. Benzamil inhibits neuronal and heterologously expressed small conductance Ca2+-activated K+ channels.  |  Castañeda, MS., et al. 2019. Neuropharmacology. 158: 107738. PMID: 31447417
  8. Cortical Foxp2 Supports Behavioral Flexibility and Developmental Dopamine D1 Receptor Expression.  |  Co, M., et al. 2020. Cereb Cortex. 30: 1855-1870. PMID: 31711176
  9. Erbin in Amygdala Parvalbumin-Positive Neurons Modulates Anxiety-like Behaviors.  |  Luo, ZY., et al. 2020. Biol Psychiatry. 87: 926-936. PMID: 31889536
  10. Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation.  |  Nimtz, L., et al. 2020. Stem Cell Res. 45: 101761. PMID: 32244191
  11. The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations.  |  Devenish, SO., et al. 2021. Neuropharmacology. 182: 108371. PMID: 33122032
  12. Distinct mechanisms of CB1 and GABAB receptor presynaptic modulation of striatal indirect pathway projections to mouse globus pallidus.  |  Sitzia, G., et al. 2023. J Physiol. 601: 195-209. PMID: 36412169
  13. Perinatal blockade of neuronal glutamine transport sex-differentially alters glutamatergic synaptic transmission and organization of neurons in the ventrolateral ventral media hypothalamus of adult rats.  |  Liang, SL., et al. 2023. J Neuroendocrinol. e13253. PMID: 36949648

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-AP5 Sodium salt, 10 mg

sc-361169
10 mg
$85.00

DL-AP5 Sodium salt, 50 mg

sc-361169A
50 mg
$334.00