Date published: 2025-9-5

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DL-α-Tocopherol (CAS 10191-41-0)

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Alternate Names:
Vitamin E
Application:
DL-α-Tocopherol is an antioxidant that protects cell membrane lipids from oxidative damage
CAS Number:
10191-41-0
Purity:
≥96%
Molecular Weight:
430.71
Molecular Formula:
C29H50O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-α-Tocopherol, referred to as vitamin E, is an antioxidant fat-soluble vitamin. It occurs naturally in numerous food sources, such as vegetable oils, nuts, and green leafy vegetables. It is worth noting that vitamin E exists in different forms, including alpha-tocopherol, beta-tocopherol, gamma-tocopherol, and delta-tocopherol. Among these, DL-α-Tocopherol is the most active form within the body and is predominantly utilized in supplements. The precise mechanism by which DL-α-Tocopherol operates is not yet fully comprehended. However, it is believed to function as an antioxidant, effectively neutralizing free radicals and safeguarding cells against damage. Additionally, DL-α-Tocopherol is thought to act as a cofactor for specific enzymes involved in lipid metabolism and other molecular processes. DL-α-Tocopherol is a physiological membrane-bound antioxidant that protects cell membrane lipids from oxidative damage by free radicals.


DL-α-Tocopherol (CAS 10191-41-0) References

  1. Serum alpha-tocopherol concentration in sheep after intramuscular injection of DL-alpha-tocopherol.  |  Njeru, CA., et al. 1992. J Anim Sci. 70: 2562-7. PMID: 1506318
  2. Effect of alpha-tocopherol and tocopherol succinate on lipid peroxidation in equine spermatozoa.  |  Almeida, J. and Ball, BA. 2005. Anim Reprod Sci. 87: 321-37. PMID: 15911181
  3. Age and gender-related reference values for serum dl-alpha-tocopherol and all-trans-retinol levels in Saudi population.  |  Al-Saleh, I., et al. 2007. Int J Vitam Nutr Res. 77: 326-35. PMID: 18453317
  4. Protective effect of dl-alpha-tocopherol on the cytotoxicity of ultraviolet B against human skin fibroblasts in vitro.  |  Kondo, S., et al. 1990. Photodermatol Photoimmunol Photomed. 7: 173-7. PMID: 2076374
  5. Dl-α-tocopherol enhances the herbicide 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat, PQ) genotoxicity in cultured anuran leukocytes.  |  Hanada, H. 2011. Hereditas. 148: 118-24. PMID: 22150823
  6. Effects of oral micellized natural vitamin E (D-α-tocopherol) v. synthetic vitamin E (DL-α-tocopherol) in feed on α-tocopherol levels, stereoisomer distribution, oxidative stress and the immune response in piglets.  |  Amazan, D., et al. 2014. Animal. 8: 410-9. PMID: 24534689
  7. Distinction of synthetic dl-α-tocopherol from natural vitamin E (d-α-tocopherol) by reversed-phase liquid chromatography. Enhanced selectivity of a polymeric C18 stationary phase at low temperature and/or at high pressure.  |  Yui, Y., et al. 2016. J Chromatogr A. 1450: 45-52. PMID: 27157422
  8. New Δ-tocotrienol derivatives from Colombian propolis.  |  Popova, MP., et al. 2020. Nat Prod Res. 34: 2779-2786. PMID: 30938183
  9. Vitamin E (α-tocopherol) consumption influences gut microbiota composition.  |  Choi, Y., et al. 2020. Int J Food Sci Nutr. 71: 221-225. PMID: 31298050
  10. Dl-alpha-tocopherol, iron, and lipofuscin in thalassemia.  |  Hyman, CB., et al. 1974. Ann N Y Acad Sci. 232: 211-20. PMID: 4528518
  11. Effect of [dl]-alpha-tocopherol on FeCl2-induced lipid peroxidation in rat amygdala.  |  Triggs, WJ. and Willmore, LJ. 1994. Neurosci Lett. 180: 33-6. PMID: 7877756
  12. dl-alpha-tocopherol induces apoptosis in erythroleukemia, prostate, and breast cancer cells.  |  Sigounas, G., et al. 1997. Nutr Cancer. 28: 30-5. PMID: 9200147
  13. Synthesis of DL-alpha-tocopherol-ligated phospholipids.  |  Stamatov, SD. 1998. Chem Phys Lipids. 91: 129-34. PMID: 9569616
  14. Antigoitrogenic effect of combined supplementation with dl-alpha-tocopherol, ascorbic acid and beta-carotene and of dl-alpha-tocopherol alone in the rat.  |  Mutaku, JF., et al. 1998. J Endocrinol. 156: 551-61. PMID: 9582512

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-α-Tocopherol, 5 g

sc-294383
5 g
$25.00

DL-α-Tocopherol, 25 g

sc-294383A
25 g
$51.00

DL-α-Tocopherol, 100 g

sc-294383B
100 g
$122.00

DL-α-Tocopherol, 500 g

sc-294383C
500 g
$320.00