Date published: 2026-5-22

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DL-α-Methylleucine (CAS 144-24-1)

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Alternate Names:
α-Me-DL-Leu-OH; (RS)-2-Amino-2,4-dimethylpentanoic acid
CAS Number:
144-24-1
Purity:
≥99%
Molecular Weight:
145.20
Molecular Formula:
C7H15NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-alpha-Methylleucine functions as a competitive inhibitor of the enzyme branched-chain amino acid aminotransferase. It interferes with the normal function of the enzyme by binding to its active site, preventing the conversion of branched-chain amino acids to their respective alpha-keto acids. By doing so, DL-alpha-Methylleucine disrupts the normal metabolic pathways of these amino acids, leading to a decrease in the production of metabolites and energy sources. This interference at the molecular level can be utilized to study the specific roles of branched-chain amino acids in cellular metabolism and to investigate the consequences of their dysregulation. In a research and development setting, DL-alpha-Methylleucine′s mode of action provides a means to manipulate cellular processes and study the resulting effects, contributing to a deeper understanding of metabolic pathways.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-α-Methylleucine, 1 g

sc-285463
1 g
$100.00

DL-α-Methylleucine, 5 g

sc-285463A
5 g
$330.00