DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt (CAS 103476-21-7)
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Alternate Names:
DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt
Application:
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt is an intermediate in biosynthesis
CAS Number:
103476-21-7
Purity:
≥95%
Molecular Weight:
977.62
Molecular Formula:
C27H41N7O20P3S•3Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) trisodium salt is a substrate employed to investigate the specificity and kinetics of the enzyme HMG-CoA reductase. This enzyme facilitates the conversion of HMG-CoA to mevalonic acid, a vital step in the synthesis of cholesterol. Moreover, HMG-CoA serves as a key intermediate in the biosynthesis of terpenes and ketone bodies, playing a significant role in the mevalonate and ketogenesis pathways.
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt (CAS 103476-21-7) References
- The effect of copper deficiency on rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. | Yount, NY., et al. 1990. J Nutr Biochem. 1: 21-7. PMID: 15539161
- Pectin isolated from prickly pear (Opuntia sp.) modifies low density lipoprotein metabolism in cholesterol-fed guinea pigs. | Fernandez, ML., et al. 1990. J Nutr. 120: 1283-90. PMID: 2231018
- Properties of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase from Pisum sativum seedlings. | Brooker, JD. and Russell, DW. 1975. Arch Biochem Biophys. 167: 723-9. PMID: 235902
- Effect of CS-514, a competitive inhibitor of hydroxymethylglutaryl coenzyme A reductase, on cholesterol gallstone formation in hamsters. | Koide, K., et al. 1989. Biochim Biophys Acta. 1005: 65-71. PMID: 2505850
- 3-Hydroxy-3-methylglutaryl-coenzyme A synthase from ox liver. Purification, molecular and catalytic properties. | Lowe, DM. and Tubbs, PK. 1985. Biochem J. 227: 591-9. PMID: 2860895
- The kinetic mechanism of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from baker's yeast. | Middleton, B. 1972. Biochem J. 126: 35-47. PMID: 4561618
- An enzyme-bound intermediate in the biosynthesis of 3-hydroxy-3-methylglutaryl-coenzyme A. | Middleton, B. and Tubbs, PK. 1974. Biochem J. 137: 15-23. PMID: 4595282
- Overproduction of a Mr 92,000 protomer of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in compactin-resistant C100 cells. | Hardeman, EC., et al. 1983. Proc Natl Acad Sci U S A. 80: 1516-20. PMID: 6572913
- Lipid composition and 3-hydroxy-3-methylglutaryl-CoA reductase activity of acinar cell carcinoma of rat pancreas. | Rao, KN., et al. 1983. Biochim Biophys Acta. 759: 74-80. PMID: 6882793
- 3-Hydroxy-3-methylglutaryl coenzyme A lyase from tissues of the oyster, Crassostrea virginica, the little skate, Raja erinacea and the lake charr, Salvelinus namaycush: a simplified spectrophotometric assay | Berges, J. A. and Ballantyne, J. S. 1989. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 93(3): 583-588.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt, 5 mg | sc-214929 | 5 mg | $350.00 | |||
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt, 10 mg | sc-214929A | 10 mg | $570.00 | |||
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt, 50 mg | sc-214929B | 50 mg | $2500.00 | |||
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt, 100 mg | sc-214929C | 100 mg | $4600.00 | |||
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt, 250 mg | sc-214929D | 250 mg | $9300.00 |