Date published: 2025-10-15

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Dithioerythritol (CAS 6892-68-8)

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Alternate Names:
erythro-1,4-Dimercapto-2,3-butanediol
Application:
Dithioerythritol is a useful reagent for maintaining sulfhydryl groups in the reduced state
CAS Number:
6892-68-8
Purity:
≥98%
Molecular Weight:
154.25
Molecular Formula:
C4H10O2S2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dithioerythritol is an epimer of dithiothreitol and an erythro isomer of 2,3-dihydroxy-1,4- dithiolbutane. The compound is a protective agent for thiol groups and strong reducing agent that is capable of reducing disulfide bonds.


Dithioerythritol (CAS 6892-68-8) References

  1. DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS.  |  CLELAND, WW. 1964. Biochemistry. 3: 480-2. PMID: 14192894
  2. A pH-metric, UV, NMR, and X-ray crystallographic study on arsenous acid reacting with dithioerythritol.  |  Kolozsi, A., et al. 2008. Inorg Chem. 47: 3832-40. PMID: 18380458
  3. Influence of methionine and dithioerythritol on sperm motility, lipid peroxidation and antioxidant capacities during liquid storage of ram semen.  |  Coyan, K., et al. 2010. Res Vet Sci. 89: 426-31. PMID: 20403626
  4. Effects of curcumin and dithioerythritol on frozen-thawed bovine semen.  |  Bucak, MN., et al. 2012. Andrologia. 44 Suppl 1: 102-9. PMID: 21729133
  5. Effects of dithioerythritol on ram semen after the freeze-thawing process.  |  Başpınar, N., et al. 2011. Cryobiology. 63: 152-6. PMID: 21945818
  6. Effects of dithiothreitol, dithioerythritol and chelating agents on 5'-nucleotidase from bull seminal plasma.  |  Fini, C., et al. 1985. Biochim Biophys Acta. 827: 403-9. PMID: 2982409
  7. Improved identification of antitrypsin phenotypes through isoelectric focusing with dithioerythritol.  |  Pierce, JA. and Eradio, BG. 1979. J Lab Clin Med. 94: 826-31. PMID: 315443
  8. Nitrate reductase from Azotobacter chroococcum. Inactivation by oxidizing agents and reactivation with dithioerythritol.  |  Vila, R., et al. 1978. Biochem Biophys Res Commun. 84: 943-9. PMID: 728161
  9. Inhibition of L-threonine intestinal absorption in rabbits by cadmium.  |  Mesonero, JE., et al. 1996. Biol Trace Elem Res. 52: 133-42. PMID: 8773754
  10. Activation of fungal alpha-amylase by dithioerythritol.  |  Ulbrich, R. and Schellenberger, A. 1979. Acta Biol Med Ger. 38: 1539-42. PMID: 95240

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dithioerythritol, 1 g

sc-202585
1 g
$63.00

Dithioerythritol, 5 g

sc-202585A
5 g
$200.00