Molecular structure of Disopyramide, CAS Number: 3737-09-5
Disopyramide (CAS 3737-09-5)
Alternate Names:
α-[2-[Bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide; Dicorantil; Ritmilen
Application:
Disopyramide is an antiarrhythmic (class IA) and a sodium channel blocker
CAS Number:
3737-09-5
Molecular Weight:
339.47
Molecular Formula:
C21H29N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Disopyramide is a compound that is often utilized in research focused on electrophysiology and cardiac function. In experimental applications, disopyramide is used to study ion channel behavior, particularly sodium and potassium channels in cardiac myocytes, which are critical for the generation and propagation of electrical signals in heart tissue. Researchers investigate the effects of disopyramide on action potential duration and refractory periods, which can provide insights into its influence on cardiac rhythm. Additionally, disopyramide is employed in the analysis of cardiomyocyte excitability and contractility, contributing to the broader understanding of the electrophysiological basis of heart function.
Disopyramide (CAS 3737-09-5) References
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- Fatal disopyramide intoxication from suicidal/accidental overdose. | Sathyavagiswaran, L. 1987. J Forensic Sci. 32: 1813-8. PMID: 3323413
- Disopyramide pharmacokinetics and metabolism: effect of inducers. | Kapil, RP., et al. 1987. Br J Clin Pharmacol. 24: 781-91. PMID: 3440098
- Clinical pharmacokinetics of disopyramide. | Siddoway, LA. and Woosley, RL. 1986. Clin Pharmacokinet. 11: 214-22. PMID: 3524956
- Disopyramide-pyridostigmine interaction: selective reversal of anticholinergic symptoms with preservation of antiarrhythmic effect. | Teichman, SL., et al. 1987. J Am Coll Cardiol. 10: 633-41. PMID: 3624669
- Disopyramide-induced ventricular tachycardia. | Lo, KS., et al. 1980. Arch Intern Med. 140: 413-4. PMID: 6153888
- Disopyramide: evaluation of electrophysiologic effects and clinical efficacy in patients with sustained ventricular tachycardia or ventricular fibrillation. | Lerman, BB., et al. 1983. Am J Cardiol. 51: 759-64. PMID: 6829435
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Disopyramide, 100 mg | sc-207585 | 100 mg | $347.00 |