Molecular structure of Disialyllacto-N-tetraose, CAS Number: 61278-38-4
Disialyllacto-N-tetraose (CAS 61278-38-4)
Alternate Names:
a-NeuNAc-(2-3)-b-Gal-(1-3)-[a-NeuNAc-(2-6)]-b-GlcNAc-(1-3)-b-Gal-(1-4)-Glc
Application:
Disialyllacto-N-tetraose is a polysaccharide
CAS Number:
61278-38-4
Purity:
≥95%
Molecular Weight:
1290.16
Molecular Formula:
C48H79N3O37
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Disialyllacto-N-tetraose is a complex carbohydrate structure that consists of four sugar units linked together. It is composed of two sialic acid residues, which are a type of sugar, attached to a lactose molecule. The sialic acid residues are connected to the lactose through a specific type of bond known as an N-glycosidic bond. Disialyllacto-N-tetraose is found in various biological systems, including human milk, where it serves as a component of human milk oligosaccharides.
Disialyllacto-N-tetraose (CAS 61278-38-4) References
- Development of photocrosslinked sialic acid containing polymers for use in Abeta toxicity attenuation. | Cowan, CB., et al. 2008. Biomaterials. 29: 3408-14. PMID: 18508118
- Determination of sialyl and neutral oligosaccharide levels in transition and mature milks of Samoan women, using anthranilic derivatization followed by reverse phase high performance liquid chromatography. | Leo, F., et al. 2010. Biosci Biotechnol Biochem. 74: 298-303. PMID: 20139617
- The human milk oligosaccharide disialyllacto-N-tetraose prevents necrotising enterocolitis in neonatal rats. | Jantscher-Krenn, E., et al. 2012. Gut. 61: 1417-25. PMID: 22138535
- Liquid chromatography/tandem mass spectrometry with fluorous derivatization method for selective analysis of sialyl oligosaccharides. | Sakaguchi, Y., et al. 2014. Rapid Commun Mass Spectrom. 28: 2481-9. PMID: 25366395
- Sialylated galacto-oligosaccharides and 2'-fucosyllactose reduce necrotising enterocolitis in neonatal rats. | Autran, CA., et al. 2016. Br J Nutr. 116: 294-9. PMID: 27212112
- What's normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically. | McGuire, MK., et al. 2017. Am J Clin Nutr. 105: 1086-1100. PMID: 28356278
- Enzymatic and Chemoenzymatic Syntheses of Disialyl Glycans and Their Necrotizing Enterocolitis Preventing Effects. | Yu, H., et al. 2017. J Org Chem. 82: 13152-13160. PMID: 29124935
- Human Milk Oligosaccharide Concentrations Are Associated with Multiple Fixed and Modifiable Maternal Characteristics, Environmental Factors, and Feeding Practices. | Azad, MB., et al. 2018. J Nutr. 148: 1733-1742. PMID: 30247646
- Analysis of Disialyllacto-N-Tetraose (DSLNT) Content in Milk From Mothers of Preterm Infants. | Hassinger, D., et al. 2020. J Hum Lact. 36: 291-298. PMID: 32109186
- Human milk fungi: environmental determinants and inter-kingdom associations with milk bacteria in the CHILD Cohort Study. | Moossavi, S., et al. 2020. BMC Microbiol. 20: 146. PMID: 32503420
- Causative role of mast cell and mast cell-regulatory function of disialyllacto-N-tetraose in necrotizing enterocolitis. | Zhang, W., et al. 2021. Int Immunopharmacol. 96: 107597. PMID: 33812262
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Disialyllacto-N-tetraose, 1 mg | sc-470854 | 1 mg | $928.00 | |||
Disialyllacto-N-tetraose, 5 mg | sc-470854A | 5 mg | $2685.00 |