Dipropofol (CAS 2416-95-7)
Alternate Names:
3,3′,5,5′-Tetraisopropyl-4,4′-dihydroxybiphenyl
CAS Number:
2416-95-7
Molecular Weight:
354.53
Molecular Formula:
C24H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Dipropofol is a sedative-hypnotic agent that acts as a positive allosteric modulator of the GABA-A receptor. It enhances the inhibitory effect of GABA by increasing the duration of the opening of the chloride channel, leading to hyperpolarization of the neuronal membrane. This results in the suppression of neuronal activity. Dipropofol can inhibit NMDA receptors and modulate the release of neurotransmitters such as dopamine and serotonin.
Dipropofol (CAS 2416-95-7) References
- Antibacterial activity of dipropofol and related compounds. | Ogata, M., et al. 2005. Biol Pharm Bull. 28: 1120-2. PMID: 15930760
- Mechanism of action of dipropofol and synergistic action with other antibacterial agents in vitro. | Ogata, M., et al. 2005. Biol Pharm Bull. 28: 1773-5. PMID: 16141558
- Solubilization of dipropofol, an antibacterial agent, using saccharide and ascorbic acid. | Ogata, M., et al. 2007. Biol Pharm Bull. 30: 1565-8. PMID: 17666822
- [Antioxidant and antibacterial activities of dimeric phenol compounds]. | Ogata, M. 2008. Yakugaku Zasshi. 128: 1149-58. PMID: 18670180
- Reaction between the anesthetic agent propofol and the free radical DPPH in semiaqueous media: kinetics and characterization of the products. | Friaa, O., et al. 2008. Free Radic Biol Med. 45: 1011-8. PMID: 18672054
- Addition of a water-soluble propofol formulation to preservation solution in experimental kidney transplantation. | Snoeijs, MG., et al. 2011. Transplantation. 92: 296-302. PMID: 21709605
- Novel propofol derivatives and implications for anesthesia practice. | Feng, AY., et al. 2017. J Anaesthesiol Clin Pharmacol. 33: 9-15. PMID: 28413268
- Anticonvulsant effect of dipropofol by enhancing native GABA currents in cortical neurons in mice. | Zhang, J., et al. 2018. J Neurophysiol. 120: 1404-1414. PMID: 29924712
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dipropofol, 10 mg | sc-497873 | 10 mg | $290.00 |