Molecular structure of DIPPMPO
DIPPMPO
Alternate Names:
5-(Diisopropoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
Application:
DIPPMPO is an efficient spin trap to detect free radicals
Purity:
98%
Molecular Weight:
263.27
Molecular Formula:
C11H22NO4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
DIPPMPO is, beside DEPMPO (sc-202132), the most efficient spin trap for the in vitro detection of O-, N-, S-, and C-centered free radicals. DIPPMPO is more lipophilic (Kp=2.1) than DEPMPO (sc-202132) with a longer life-time than DMPO (sc-202587).
DIPPMPO References
- The line asymmetry of electron spin resonance spectra as a tool to determine the cis:trans ratio for spin-trapping adducts of chiral pyrrolines N-oxides: the mechanism of formation of hydroxyl radical adducts of EMPO, DEPMPO, and DIPPMPO in the ischemic-reperfused rat liver. | Culcasi, M., et al. 2006. Free Radic Biol Med. 40: 1524-38. PMID: 16632113
- Characterization of free radical spin adducts of the DIPPMPO using mass spectrometry and (31)P NMR. | Zoia, L. and Argyropoulos, DS. 2010. Eur J Mass Spectrom (Chichester). 16: 175-85. PMID: 20212327
- Understanding the radical mechanism of lipoxygenases using 31P NMR spin trapping. | Zoia, L., et al. 2011. Bioorg Med Chem. 19: 3022-8. PMID: 21474321
- Detection of superoxide production in stimulated and unstimulated living cells using new cyclic nitrone spin traps. | Abbas, K., et al. 2014. Free Radic Biol Med. 71: 281-290. PMID: 24662195
- Mitochondria-targeted spin traps: synthesis, superoxide spin trapping, and mitochondrial uptake. | Hardy, M., et al. 2014. Chem Res Toxicol. 27: 1155-65. PMID: 24890552
- Medium-throughput ESR detection of superoxide production in undetached adherent cells using cyclic nitrone spin traps. | Abbas, K., et al. 2015. Free Radic Res. 49: 1122-8. PMID: 25968949
- Detection of Hydroxyl and Perhydroxyl Radical Generation from Bleaching Agents with Nuclear Magnetic Resonance Spectroscopy. | Sharma, H. and Sharma, DS. 2017. J Clin Pediatr Dent. 41: 126-134. PMID: 28288300
- Comparison of different methods for measuring the superoxide radical by EPR spectroscopy in buffer, cell lysates and cells. | Scheinok, S., et al. 2018. Free Radic Res. 52: 1182-1196. PMID: 30362382
- Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals. | Besson, E., et al. 2019. Analyst. 144: 4194-4203. PMID: 31180410
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DIPPMPO, 50 mg | sc-221551 | 50 mg | $213.00 |