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Diphenyltin dichloride (CAS 1135-99-5)

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Alternate Names:
Dichlorodiphenyltin
CAS Number:
1135-99-5
Purity:
≥94%
Molecular Weight:
343.82
Molecular Formula:
C12H10Cl2Sn
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diphenyltin dichloride is a chemical compound that functions as a catalyst in organic synthesis. Its mechanism of action involves facilitating the formation of carbon-carbon and carbon-heteroatom bonds through its interaction with specific functional groups in the substrate molecules. Diphenyltin Dichloride acts as a Lewis acid, promoting the activation of certain chemical bonds and enabling the desired reactions to proceed efficiently. In the experimental, diphenyltin dichloride plays a role in promoting the synthesis of various organic compounds by facilitating key bond-forming steps. Its mechanism of action involves the coordination of the tin atom with electron-rich groups in the substrate, leading to the activation of specific chemical bonds and subsequent bond formation. Diphenyltin Dichloride′s function in organic synthesis involves its ability to promote the desired chemical transformations by interacting with the reactive sites in the substrate molecules.


Diphenyltin dichloride (CAS 1135-99-5) References

  1. Adverse effects of diphenyltin dichloride on initiation and maintenance of pregnancy in rats.  |  Ema, M., et al. 1999. Toxicol Lett. 108: 17-25. PMID: 10472806
  2. Trypanocidal activity of organotin chlorides on Trypanosoma brucei-infected mice.  |  Shuaibu, MN., et al. 2000. Parasite. 7: 43-5. PMID: 10743647
  3. Suppression of uterine decidualization correlated with reduction in serum progesterone levels as a cause of preimplantation embryonic loss induced by diphenyltin in rats.  |  Ema, M. and Miyawaki, E. 2002. Reprod Toxicol. 16: 309-17. PMID: 12128105
  4. Antioxidative effect of kaempferol and its equimolar mixture with phenyltin compounds on UV-irradiated liposome membranes.  |  Gabrielska, J., et al. 2005. J Agric Food Chem. 53: 76-83. PMID: 15631512
  5. Inhibitory effects of phenyltin compounds on stimulus-induced changes in cytosolic free calcium and plasma membrane potential of human neutrophils.  |  Miura, Y. and Matsui, H. 1991. Arch Toxicol. 65: 562-9. PMID: 1664201
  6. Antioxidative effect of quercetin and its equimolar mixtures with phenyltin compounds on liposome membranes.  |  Gabrielska, J., et al. 2006. J Agric Food Chem. 54: 7735-46. PMID: 17002447
  7. Synthetic, structural, and biochemical studies of organotin(IV) with Schiff bases having nitrogen and sulphur donor ligands.  |  Singh, HL. and Varshney, AK. 2006. Bioinorg Chem Appl. 2006: 23245. PMID: 17497003
  8. Understanding the molecular behavior of organotin compounds to design their effective use as agrochemicals: exploration via quantum chemistry and experiments.  |  Ramalho, TC., et al. 2010. J Biomol Struct Dyn. 28: 227-38. PMID: 20645655
  9. Speciation studies of diorganotin(IV) complexes with 3,3-bis(1-methylimidazol-2-yl)propionate--displacement reaction by DNA constituents.  |  Shoukry, MM. and Hassan, SS. 2013. ScientificWorldJournal. 2013: 106357. PMID: 24385867
  10. Synthesis of Stannole-Containing π-Conjugated Polymers by Post-Element Transformation of Organotitanium Polymer.  |  Matsumura, Y., et al. 2019. Macromol Rapid Commun. 40: e1800929. PMID: 31150134
  11. New Tailored RNA-Targeted Organometallic Drug Candidates against Huh7 (Liver) and Du145 (Prostate) Cancer Cell Lines.  |  Khan, HY., et al. 2020. ACS Omega. 5: 15218-15228. PMID: 32637795
  12. Ciprofloxacin conjugated to diphenyltin(IV): a novel formulation with enhanced antimicrobial activity.  |  Chrysouli, MP., et al. 2020. Dalton Trans. 49: 11522-11535. PMID: 32656556
  13. Influence of organotins on rat platelet aggregation mechanisms.  |  Knowles, CO. and Johnson, TL. 1986. Environ Res. 39: 172-9. PMID: 3943507
  14. [Effect of triphenyltin chloride on superoxide (O2-.) production in human neutrophils].  |  Matsui, H., et al. 1984. Sangyo Igaku. 26: 165-9. PMID: 6094890

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diphenyltin dichloride, 5 g

sc-223949
5 g
$37.00

Diphenyltin dichloride, 25 g

sc-223949A
25 g
$141.00