Date published: 2025-10-14

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Diphenyl ether (CAS 101-84-8)

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Alternate Names:
Diphenyl oxide; Phenyl ether
CAS Number:
101-84-8
Molecular Weight:
170.21
Molecular Formula:
C12H10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diphenyl ether functions as a heat transfer medium and a solvent in various experimental applications. It is able to facilitate the transfer of heat in a controlled manner, making it useful in experimental setups that require precise temperature regulation. At the molecular level, diphenyl ether interacts with other compounds to effectively transfer heat energy, contributing to the overall thermal management of the system. Its mechanism of action involves forming stable interactions with surrounding molecules, allowing for efficient heat exchange without undergoing significant chemical changes itself. This property makes diphenyl ether a useful component in experimental setups that require consistent and controlled thermal conditions.


Diphenyl ether (CAS 101-84-8) References

  1. Polyketide butenolide, diphenyl ether, and benzophenone derivatives from the fungus Aspergillus flavipes PJ03-11.  |  Zhang, LH., et al. 2016. Bioorg Med Chem Lett. 26: 346-350. PMID: 26706176
  2. Potentials of Diphenyl Ether Scaffold as a Therapeutic Agent: A Review.  |  Kini, SG., et al. 2019. Mini Rev Med Chem. 19: 1392-1406. PMID: 30864517
  3. Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop.  |  Bueno, O., et al. 2019. Eur J Med Chem. 171: 195-208. PMID: 30921759
  4. RIFM fragrance ingredient safety assessment, diphenyl ether, CAS Registry Number 101-84-8.  |  Api, AM., et al. 2019. Food Chem Toxicol. 134 Suppl 1: 110632. PMID: 31238135
  5. Antibacterial Diphenyl Ether, Benzophenone and Xanthone Derivatives from Aspergillus flavipes.  |  Ji, YB., et al. 2020. Chem Biodivers. 17: e1900640. PMID: 31805214
  6. A new diphenyl ether from Parmotrema indicum Hale growing in Vietnam.  |  Do, TH., et al. 2022. Nat Prod Res. 36: 4879-4885. PMID: 33823690
  7. Thermal treatment of decabrominated diphenyl ether in its highly contaminated soil in Taiwan.  |  Ko, CF., et al. 2022. Chemosphere. 287: 131924. PMID: 34492411
  8. Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp. YS-1 and characterization of two initial degrading esterases.  |  Shang, N., et al. 2022. Sci Total Environ. 806: 151357. PMID: 34742792
  9. Design, Synthesis, and Herbicidal Activity of Diphenyl Ether Derivatives Containing a Five-Membered Heterocycle.  |  Zhao, LX., et al. 2022. J Agric Food Chem. 70: 1003-1018. PMID: 35040327
  10. Neopestolides A-D, Diphenyl Ether Derivatives from the Plant Endophytic Fungus Neopestalotiopsis sp.  |  Li, C., et al. 2022. J Nat Prod. 85: 607-613. PMID: 35049297
  11. Antibacterial diphenyl ether production induced by co-culture of Aspergillus nidulans and Aspergillus fumigatus.  |  Ninomiya, A., et al. 2022. Appl Microbiol Biotechnol. 106: 4169-4185. PMID: 35595930
  12. Four new diphenyl ether derivatives from a mangrove endophytic fungus Epicoccum sorghinum.  |  Zhu, JJ., et al. 2022. Chin J Nat Med. 20: 537-540. PMID: 35907652
  13. Synthesis and Self-assembly of Novel Nanofeather-like Fluorescent Alkyloxy-Containing Diphenyl Ether Organogelators.  |  Abualnaja, MM., et al. 2022. ACS Omega. 7: 34309-34316. PMID: 36188290
  14. Discovery of diphenyl ether-degrading Streptomyces strains by direct screening based on ether bond-cleaving activity.  |  Tonegawa, S., et al. 2023. J Biosci Bioeng. 135: 474-479. PMID: 36973095

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diphenyl ether, 5 g

sc-234778
5 g
$46.00