Molecular structure of Diphenyl-1-pyrenylphosphine, CAS Number: 110231-30-6
Diphenyl-1-pyrenylphosphine (CAS 110231-30-6)
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Alternate Names:
DPPP; 1-(Diphenylphosphino)pyrene
Application:
Diphenyl-1-pyrenylphosphine is a fluoregenic peroxide reactive probe
CAS Number:
110231-30-6
Molecular Weight:
386.43
Molecular Formula:
C28H19P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Diphenyl-1-pyrenylphosphine (DPPP) is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O).1 Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidylethanolamine, triglycerides, and cholesteryl esters have been measured by HPLC with a post column detection system using DPPP.2,3 DPPP has also been used as a fluorescent probe for the detection of low density lipoprotein and cellular oxidation.4 Fluorescence of DPPP-O can be monitor using excitation and emission wavelengths of 351 nm and 380 nm, respectively.
Diphenyl-1-pyrenylphosphine (CAS 110231-30-6) References
1 Okimoto, Y., Watanabe, A., Niki, E., et al. A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes. FEBS Lett 474 137-140 (2000). 2 Alasaka, K., Ijichi, S., Watanabe, K., et al. High performance liquid chromatography and post column derivatization with DPPP for fluorometric determination of triglycerol hydropeoxides. J Chromatogr 596 197-202 (1992). 3 Akassaka, K., Ijichi, S., Ohrui, H., et al. Simultaneous determination of hydroperoxides of phosphotidylcholine, cholesterol esters and triglycerols by column-switiching HPLC witha postcolumn detection system. J Chromatogr 622 153-159 (1993). 4 Okimoto, Y., Warabi, E., Wada, Y., et al. A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine. Free Radic Biol Med 35(6) 576-585 (2003).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diphenyl-1-pyrenylphosphine, 5 mg | sc-205293 | 5 mg | $275.00 | |||
Diphenyl-1-pyrenylphosphine, 10 mg | sc-205293A | 10 mg | $530.00 |