Date published: 2026-5-1

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Dipeptidylpeptidase IV Inhibitor III (CAS 866396-34-1)

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Alternate Names:
1-(((1-(Hydroxymethyl)cyclopentyl)amino)acetyl)-2,5-cis-pyrrolidinedicarbonitrile;Dipeptidyl peptidase IV Inhibitor III
Application:
Dipeptidylpeptidase IV Inhibitor III is a slow-binding and active site-targeting inhibitor of CD26
CAS Number:
866396-34-1
Molecular Weight:
312.80
Molecular Formula:
C14H20N4O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Dipeptidylpeptidase IV Inhibitor III is a dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of CD26 (DPP 4), with an IC50 = 106 nM and little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 muM.


Dipeptidylpeptidase IV Inhibitor III (CAS 866396-34-1) References

  1. LAF-237 (Novartis).  |  Barlocco, D. 2004. Curr Opin Investig Drugs. 5: 1094-100. PMID: 15535431

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dipeptidylpeptidase IV Inhibitor III, 5 mg

sc-202582
5 mg
$450.00
US: Only available in the US