dinitrophenyl Antibody (LO-DNP-30): sc-80770

Dinitrophenyl Antibody (LO-DNP-30) is a rat monoclonal IgE antibody that detects dinitrophenyl in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Dinitrophenyl is a synthetic cellular metabolic poison known for uncoupling oxidative phosphorylation, acting as a proton ionophore that facilitates proton transport across mitochondrial membranes. This mechanism leads to rapid energy depletion without adenosine triphosphate (ATP) production, resulting in proton gradient dissipation as heat. Dinitrophenyl′s significance lies in disrupting normal cellular energy metabolism, making dinitrophenyl a valuable tool in biochemistry research for investigating bioenergetics regulation across organisms. Additionally, dinitrophenyl is recognized as an environmental contaminant, released into the atmosphere through automobile exhaust and industrial processes, raising concerns about human health and ecological system impacts. Anti-dinitrophenyl antibody (LO-DNP-30) provides researchers a reliable means to detect and quantify dinitrophenyl in various experimental settings.

The preferred dinitrophenyl antibody is dinitrophenyl Antibody (10.12): sc-69698.