dinitrophenyl Antibody (26.82): sc-69695

Dinitrophenyl Antibody (26.82) is a mouse monoclonal IgE antibody that detects dinitrophenyl in non-species specific samples by enzyme-linked immunosorbent assay (ELISA). Dinitrophenyl is a synthetic cellular metabolic poison that plays a significant role in biochemistry research due to its ability to uncouple oxidative phosphorylation by acting as a proton ionophore, which facilitates the transport of protons across the mitochondrial membrane. This mechanism leads to a rapid depletion of energy without the generation of adenosine triphosphate (ATP), resulting in the dissipation of the proton gradient as heat. Understanding dinitrophenyl′s function is crucial, as dinitrophenyl not only serves as an environmental contaminant—polluting air through sources such as automobile exhaust and industrial processes—but also provides insights into the regulation of bioenergetics across various organisms. Commercial applications of dinitrophenyl extend beyond scientific research, having been utilized historically in photographic development, dye production, wood preservation, explosives, and pest control, making dinitrophenyl a versatile compound in both environmental and industrial contexts. Anti-dinitrophenyl antibody (26.82) serves as an essential tool for researchers investigating the intricate dynamics of energy metabolism and its implications in various biological systems.

The preferred dinitrophenyl antibody is dinitrophenyl Antibody (10.12): sc-69698.