Date published: 2025-9-5

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Dimethylphosphinic acid (CAS 3283-12-3)

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CAS Number:
3283-12-3
Molecular Weight:
94.05
Molecular Formula:
C2H7O2P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dimethylphosphinic acid (DMPA) is an organic compound derived from phosphinic acid. It presents itself as a colorless, odorless solid that exhibits solubility in both water and a wide range of organic solvents. It encompasses a broad spectrum of biochemical and physiological effects and is utilized as a reagent and catalyst in laboratory experiments. In the field of biotechnology, Dimethylphosphinic acid contributes to the synthesis of proteins, enzymes, and other biomolecules. Additionally, it plays a significant role in the synthesis of nanoparticles. As a catalyst, Dimethylphosphinic acid actively participates in numerous organic reactions. Its strong acidic properties allow it to protonate a wide array of compounds, including alcohols, carboxylic acids, amines, and other substrates. The protonated compounds subsequently engage in diverse reactions, depending on the nature of the substrates and the prevailing reaction conditions.


Dimethylphosphinic acid (CAS 3283-12-3) References

  1. Structural and Spectroscopic Studies of Two Phases of the Organometallic Chain Polymer [Ru(2){&mgr;(2):&mgr;(2):eta(2)-O(2)PMe(2)}(2)(CO)(4)](n)().  |  Barnes, CM., et al. 1997. Inorg Chem. 36: 5793-5798. PMID: 11670201
  2. Solvent dependent reactivity: solvent activation vs. solvent coordination in alkylphosphane iron complexes.  |  Kohl, SW., et al. 2006. Dalton Trans. 5583-92. PMID: 17225895
  3. Dimethylphosphinate bridged binuclear Rh(i) catalysts for the alkoxycarbonylation of aromatic C-H bonds.  |  Iturmendi, A., et al. 2016. Dalton Trans. 45: 16955-16965. PMID: 27722359
  4. From Well-Defined Alkylzinc Phosphinates to Quantum-Sized ZnO Nanocrystals.  |  Wolska-Pietkiewicz, M., et al. 2017. Chemistry. 23: 11856-11865. PMID: 28657662
  5. Influence of Hydrogen Bonds in 1:1 Complexes of Phosphinic Acids with Substituted Pyridines on 1H and 31P NMR Chemical Shifts.  |  Giba, IS., et al. 2019. J Phys Chem A. 123: 2252-2260. PMID: 30807160
  6. Conformational Mobility and Proton Transfer in Hydrogen-Bonded Dimers and Trimers of Phosphinic and Phosphoric Acids.  |  Mulloyarova, VV., et al. 2019. J Phys Chem A. 123: 6761-6771. PMID: 31305076
  7. Ionic Dissociation of SiCl4 : Formation of [SiL6 ]Cl4 with L=Dimethylphosphinic Acid.  |  Kowalke, J., et al. 2020. Chemistry. 26: 8003-8006. PMID: 32511798

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dimethylphosphinic acid, 100 mg

sc-234762
100 mg
$54.00