Date published: 2025-10-2

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Dimethylphenylphosphine (CAS 672-66-2)

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Alternate Names:
Phenyldimethylphosphine; Me2PPh
CAS Number:
672-66-2
Molecular Weight:
138.15
Molecular Formula:
(CH3)2PC6H5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dimethylphenylphosphine is an organometallic compound belonging to the P2 group. It is used in synthesizing metal carbonyls and various other compounds. Notably, Dimethylphenylphosphine has the ability to form stable complexes with fatty acids, and has been used as an intermediate for the synthesis of diverse organic compounds. Moreover, this compound serves as a ligand in transition metal complexes.


Dimethylphenylphosphine (CAS 672-66-2) References

  1. Intramolecular Nucleophilic Substitution of ω-Haloalkylphosphine Derivatives.  |  Woźnicki, P., et al. 2017. J Org Chem. 82: 10271-10296. PMID: 28857562
  2. Hyperbranched Aliphatic Polyester via Cross-Metathesis Polymerization: Synthesis and Postpolymerization Modification.  |  Zeng, FR., et al. 2018. Macromol Rapid Commun. 39: PMID: 29250866
  3. Evaluating Nucleophile Byproduct Formation during Phosphine- and Amine-Promoted Thiol-Methyl Acrylate Reactions.  |  Frayne, SH. and Northrop, BH. 2018. J Org Chem. 83: 10370-10382. PMID: 30132329
  4. Trans-Pd/Pt(II) saccharinate complexes with a phosphine ligand: Synthesis, cytotoxicity and structure-activity relationship.  |  Icsel, C., et al. 2020. Bioorg Med Chem Lett. 30: 127077. PMID: 32156495
  5. ESI-MS Identification of the Cationic Phosphine-Ligated Gold Clusters Au1-22: Insight into the Gold-Ligand Ratio and Abundance of Larger Clusters.  |  Hewitt, MA., et al. 2021. J Am Soc Mass Spectrom. 32: 237-246. PMID: 33119279
  6. Sugar-Based Polymers with Stereochemistry-Dependent Degradability and Mechanical Properties.  |  Stubbs, CJ., et al. 2022. J Am Chem Soc. 144: 1243-1250. PMID: 35029980
  7. Development of Mild Chemical Catalysis Conditions for m1A-to-m6A Rearrangement on RNA.  |  Liu, H., et al. 2022. ACS Chem Biol. 17: 1334-1342. PMID: 35593877
  8. Anionic polymerization of nonaromatic maleimide to achieve full-color nonconventional luminescence.  |  Ji, X., et al. 2022. Nat Commun. 13: 3717. PMID: 35764631
  9. Late-Stage Carbon-14 Labeling and Isotope Exchange: Emerging Opportunities and Future Challenges.  |  Babin, V., et al. 2022. JACS Au. 2: 1234-1251. PMID: 35783167
  10. Click Step-Growth Polymerization and E/Z Stereochemistry Using Nucleophilic Thiol-yne/-ene Reactions: Applying Old Concepts for Practical Sustainable (Bio)Materials.  |  Worch, JC. and Dove, AP. 2022. Acc Chem Res. 55: 2355-2369. PMID: 36006902
  11. Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery.  |  Wang, X., et al. 2023. Nat Protoc. 18: 265-291. PMID: 36316378
  12. Facile Synthesis of Light-Switchable Polymers with Diazocine Units in the Main Chain.  |  Li, S., et al. 2023. Polymers (Basel). 15: PMID: 36904547
  13. A library of new organofunctional silanes obtained by thiol-(meth)acrylate Michael addition reaction.  |  Przybylska, A., et al. 2023. RSC Adv. 13: 14010-14017. PMID: 37181512

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dimethylphenylphosphine, 1 g

sc-257366
1 g
$46.00

Dimethylphenylphosphine, 5 g

sc-257366A
5 g
$152.00