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Dimethyldioctadecylammonium bromide (CAS 3700-67-2)

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Alternate Names:
Distearyldimethylammonium bromide
CAS Number:
3700-67-2
Purity:
≥98%
Molecular Weight:
630.95
Molecular Formula:
C38H80BrN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dimethyldioctadecylammonium bromide, an alkyldimethylammonium compound, finds extensive use in scientific research and laboratory experiments. As a cationic surfactant, it exhibits amphiphilic properties with both hydrophilic and hydrophobic groups. This versatile molecule serves as a potent biocide against various microorganisms, including bacteria, fungi, and viruses. Additionally, it acts as an efficient emulsifier, stabilizing oil-in-water emulsions.


Dimethyldioctadecylammonium bromide (CAS 3700-67-2) References

  1. Protective antiviral immune responses to pseudorabies virus induced by DNA vaccination using dimethyldioctadecylammonium bromide as an adjuvant.  |  van Rooij, EM., et al. 2002. J Virol. 76: 10540-5. PMID: 12239334
  2. Subunit vaccines: distearoylphosphatidylcholine-based liposomes entrapping antigen offer a neutral alternative to dimethyldioctadecylammonium-based cationic liposomes as an adjuvant delivery system.  |  McNeil, SE., et al. 2011. J Pharm Sci. 100: 1856-65. PMID: 21374619
  3. Antibacterial resistance, macrophage influx, and activation induced by bacterial rRNA with dimethyldioctadecylammonium bromide.  |  Gonggrijp, R., et al. 1985. Infect Immun. 50: 728-33. PMID: 2415454
  4. Th1 immune responses can be modulated by varying dimethyldioctadecylammonium and distearoyl-sn-glycero-3-phosphocholine content in liposomal adjuvants.  |  Hussain, MJ., et al. 2014. J Pharm Pharmacol. 66: 358-66. PMID: 24251796
  5. Interactions of Lipid Polar Headgroups with Carbendazim Fungicide.  |  Furini, LN., et al. 2019. J Nanosci Nanotechnol. 19: 3734-3743. PMID: 30764929
  6. T-cell-independent macrophage activation in mice induced with rRNA from Listeria monocytogenes and dimethyldioctadecylammonium bromide.  |  van den Bosch, JF., et al. 1986. Infect Immun. 53: 611-5. PMID: 3091505
  7. Effect of salts on size and morphology of extruded dimethyldioctadecylammonium bromide or chloride vesicle for polymeric nanocapsules synthesis via templating emulsion polymerization.  |  Rusli, W. and van Herk, AM. 2021. J Colloid Interface Sci. 587: 393-401. PMID: 33370661
  8. Immunological Effects of Dimethyldioctadecylammonium Bromide and Saponin as Adjuvants for Outer Membrane Vesicles from Neisseria meningitidis.  |  Correa, VA., et al. 2022. Diseases. 10: PMID: 35892740
  9. Biopolymer Lipid Hybrid Microcarrier for Transmembrane Inner Ear Delivery of Dexamethasone.  |  Dindelegan, MG., et al. 2022. Gels. 8: PMID: 36005084
  10. Transfer of enhanced resistance against Listeria monocytogenes induced with ribosomal RNA and the adjuvant dimethyldioctadecylammonium bromide.  |  Antonissen, AC., et al. 1986. Immunol Lett. 14: 21-8. PMID: 3804382
  11. Effect of dimethyldioctadecylammonium bromide induced macrophages on malignant cell proliferation.  |  Prager, MD., et al. 1985. Cancer Lett. 27: 225-32. PMID: 4005832
  12. Impaired macrophage functions as a possible basis of immunomodification by microbial agents, tilorone and dimethyldioctadecylammonium bromide.  |  Bloksma, N., et al. 1983. Antonie Van Leeuwenhoek. 49: 13-22. PMID: 6351737
  13. Effects of dimethyldioctadecylammonium bromide on phagocytosis and digestion of Listeria monocytogenes by mouse peritoneal macrophages.  |  Hofhuis, FM., et al. 1981. Immunology. 43: 425-31. PMID: 6788683
  14. The enhancement of humoral and cellular immune responses by dimethyldioctadecylammonium bromide.  |  Gordon, WC., et al. 1980. Cell Immunol. 49: 329-40. PMID: 6986203
  15. Interaction of antigens with dimethyldioctadecylammonium bromide, a chemically defined biological response modifier.  |  Baechtel, FS. and Prager, MD. 1982. Cancer Res. 42: 4959-63. PMID: 7139599

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dimethyldioctadecylammonium bromide, 5 g

sc-239789
5 g
$136.00

Dimethyldioctadecylammonium bromide, 25 g

sc-239789A
25 g
$514.00

Dimethyldioctadecylammonium bromide, 100 g

sc-239789B
100 g
$966.00

Dimethyldioctadecylammonium bromide, 500 g

sc-239789C
500 g
$2383.00

Dimethyldioctadecylammonium bromide, 1 kg

sc-239789D
1 kg
$4162.00