Date published: 2025-9-16

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Dimethyl trisulfide (CAS 3658-80-8)

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CAS Number:
3658-80-8
Purity:
≥98%
Molecular Weight:
126.26
Molecular Formula:
CH3SSSCH3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dimethyl trisulfide is a utilized organosulfur compound within the scientific research community. Its insolubility in water makes it a suitable substance for various experimental setups. In vitro studies have demonstrated its utility in investigating the impact of sulfur-containing compounds on cell cultures. Dimethyl trisulfide is thought to function as a chelating agent, forming complexes with metallic ions and neighboring molecules. This unique binding ability may influence the structure and function of proteins and other molecular components in its vicinity.


Dimethyl trisulfide (CAS 3658-80-8) References

  1. Dimethyl trisulfide as a characteristic odor associated with fungating cancer wounds.  |  Shirasu, M., et al. 2009. Biosci Biotechnol Biochem. 73: 2117-20. PMID: 19734656
  2. Dimethyl trisulfide: A novel cyanide countermeasure.  |  Rockwood, GA., et al. 2016. Toxicol Ind Health. 32: 2009-2016. PMID: 26939832
  3. Determination of dimethyl trisulfide in rabbit blood using stir bar sorptive extraction gas chromatography-mass spectrometry.  |  Manandhar, E., et al. 2016. J Chromatogr A. 1461: 10-7. PMID: 27477518
  4. Analgesic effect of dimethyl trisulfide in mice is mediated by TRPA1 and sst4 receptors.  |  Pozsgai, G., et al. 2017. Nitric Oxide. 65: 10-21. PMID: 28137611
  5. Reaction of Dimethyl Trisulfide with Hemoglobin.  |  Dong, X., et al. 2017. Chem Res Toxicol. 30: 1661-1663. PMID: 28809548
  6. Monitoring Dose Response of Cyanide Antidote Dimethyl Trisulfide in Rabbits Using Diffuse Optical Spectroscopy.  |  Lee, J., et al. 2018. J Med Toxicol. 14: 295-305. PMID: 30094773
  7. Intramuscular dimethyl trisulfide: efficacy in a large swine model of acute severe cyanide toxicity.  |  Hendry-Hofer, TB., et al. 2019. Clin Toxicol (Phila). 57: 265-270. PMID: 30306816
  8. Methemoglobin Forming Effect of Dimethyl Trisulfide in Mice.  |  Kiss, M., et al. 2018. Hemoglobin. 42: 315-319. PMID: 30747047
  9. Behavioural and physiological assessments of dimethyl trisulfide treatment for acute oral sodium cyanide poisoning.  |  Rice, NC., et al. 2019. Basic Clin Pharmacol Toxicol. 125: 289-303. PMID: 30843331
  10. In vitro antifungal activity of dimethyl trisulfide against Colletotrichum gloeosporioides from mango.  |  Tang, L., et al. 2019. World J Microbiol Biotechnol. 36: 4. PMID: 31832786
  11. Mutagenesis, breeding, and characterization of sake yeast strains with low production of dimethyl trisulfide precursor.  |  Makimoto, J., et al. 2020. J Biosci Bioeng. 130: 610-615. PMID: 32800812
  12. Dimethyl Trisulfide Diminishes Traumatic Neuropathic Pain Acting on TRPA1 Receptors in Mice.  |  Dombi, Á., et al. 2021. Int J Mol Sci. 22: PMID: 33806000
  13. A novel aqueous dimethyl trisulfide formulation is effective at low doses against cyanide toxicity in non-anesthetized mice and rats.  |  Lippner, DS., et al. 2022. Clin Toxicol (Phila). 60: 83-94. PMID: 34219566
  14. Efficacy of Dimethyl Trisulfide on the Suppression of Ring Rot Disease Caused by Botryosphaeria dothidea and Induction of Defense-Related Genes on Apple Fruits.  |  Sun, M., et al. 2022. Front Microbiol. 13: 796167. PMID: 35197948
  15. The Inhibitory Effect of Pseudomonas stutzeri YM6 on Aspergillus flavus Growth and Aflatoxins Production by the Production of Volatile Dimethyl Trisulfide.  |  Gong, AD., et al. 2022. Toxins (Basel). 14: PMID: 36422962

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dimethyl trisulfide, 10 mg

sc-234745
10 mg
$74.00