Molecular structure of Dimethyl dicarbonate, CAS Number: 4525-33-1
Dimethyl dicarbonate (CAS 4525-33-1)
See product citations (4)
Alternate Names:
Methoxycarbonyl methyl carbonate; DMPC; Dimethyl pyrocarbonate
Application:
Dimethyl dicarbonate is a histidine methylator
CAS Number:
4525-33-1
Molecular Weight:
134.09
Molecular Formula:
C4H6O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Dimethyl dicarbonate methylates histidine residues at the active site of PEP carboxykinase, resulting in a partially reversible inhibition. Dimethyl dicarbonate serves as a vital linear calibration curve standard in the analysis of sodium carbonate and other alkaline substances. Its production involves the reaction of ethylene diamine with sodium dicarbonate in the presence of an acid, such as acetic acid. This reaction mixture comprises methyl ethyl ketone, dimethyl carbonate, and water. Notably, dimethyl dicarbonate possesses notable antimicrobial properties, rendering it highly effective against a wide range of bacteria, fungi, and yeasts. Consequently, it finds application as a preservative in reactive solutions and as an ingredient in cosmetics, effectively inhibiting bacterial growth.
Dimethyl dicarbonate (CAS 4525-33-1) References
- Fermentability of grape must after inhibition with dimethyl dicarbonate (DMDC). | Delfini, C., et al. 2002. J Agric Food Chem. 50: 5605-11. PMID: 12236685
- Evaluation of the inhibitory effect of dimethyl dicarbonate (DMDC) against wine microorganisms. | Costa, A., et al. 2008. Food Microbiol. 25: 422-7. PMID: 18206786
- Advances in the control of wine spoilage by Zygosaccharomyces and Dekkera/Brettanomyces. | Zuehlke, JM., et al. 2013. Annu Rev Food Sci Technol. 4: 57-78. PMID: 23215631
- Inactivation of Alicyclobacillus acidoterrestris using high pressure homogenization and dimethyl dicarbonate. | Chen, W., et al. 2013. J Food Prot. 76: 1041-5. PMID: 23726202
- Combined effect of dimethyl dicarbonate (DMDC) and nisin on indigenous microorganisms of litchi juice and its microbial shelf life. | Yu, Y., et al. 2013. J Food Sci. 78: M1236-41. PMID: 23957413
- Influence of dimethyl dicarbonate on the resistance of Escherichia coli to a combined UV-Heat treatment in apple juice. | Gouma, M., et al. 2015. Front Microbiol. 6: 501. PMID: 26042117
- Improvement of wine aromatic quality using mixtures of lysozyme and dimethyl dicarbonate, with low SO2 concentration. | Nieto-Rojo, R., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 1965-75. PMID: 26374496
- Effect of High Pressure Homogenization and Dimethyl Dicarbonate (DMDC) on Microbial and Physicochemical Qualities of Mulberry Juice. | Yu, Y., et al. 2016. J Food Sci. 81: M702-8. PMID: 26764561
- Effects of reduced levels of sulfite in wine production using mixtures with lysozyme and dimethyl dicarbonate on levels of volatile and biogenic amines. | Ancín-Azpilicueta, C., et al. 2016. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 33: 1518-1526. PMID: 27597233
- The spoilage yeast Zygosaccharomyces bailii: Foe or friend? | Kuanyshev, N., et al. 2017. Yeast. 34: 359-370. PMID: 28556381
- Inactivation of Salmonella enterica and spoilage microorganisms in orange juice treated with dimethyl dicarbonate (DMDC). | Cheng, RM., et al. 2018. Int J Food Microbiol. 285: 152-157. PMID: 30153527
- The combined effect of high pressure processing and dimethyl dicarbonate to inactivate foodborne pathogens in apple juice. | Petrus, RR., et al. 2020. Braz J Microbiol. 51: 779-785. PMID: 31452069
- Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes. | Iosub, AV., et al. 2019. Org Lett. 21: 7804-7808. PMID: 31545059
- Dimethyl Dicarbonate as a Food Additive Effectively Inhibits Geotrichum citri-aurantii of Citrus. | Liu, S., et al. 2022. Foods. 11: PMID: 35954094
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Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dimethyl dicarbonate, 100 ml | sc-214900 | 100 ml | $158.00 |