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Dimethicone (CAS 9006-65-9)

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Alternate Names:
Belsil DM 1 Plus; Clearocast 100; DC 100-350CS
CAS Number:
9006-65-9
Molecular Formula:
C3H9Si(C2H6OSi)nCH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dimethicone, a silicon-based polymer, is widely recognized for its role as a lubricant and conditioning agent in various research applications, particularly those involving the study of surface properties and interactions. Due to its unique viscoelastic properties, dimethicone is instrumental in investigations focused on the modulation of surface tension and the creation of protective barriers on substrates. This polymer operates by forming a non-reactive film, which can be in experiments that require the stabilization of liquid interfaces or the reduction of friction between solid surfaces. Its effectiveness in these areas makes it a valuable component in the exploration of material science and engineering, contributing to a deeper understanding of surface dynamics and material behaviors under various conditions. In research, dimethicone′s inert nature and resistance to both water and air make it an excellent candidate for studies aimed at developing advanced coatings and lubricants, showcasing its versatility and importance beyond its physical characteristics.


Dimethicone (CAS 9006-65-9) References

  1. Quantitative determination of dimethicone in commercial tablets and capsules by Fourier transform infrared spectroscopy and antifoaming activity test.  |  Torrado, G., et al. 1999. J Pharm Biomed Anal. 19: 285-92. PMID: 10704093
  2. Dimethicone barrier cream prevents infection of human skin by schistosome cercariae: evidence from Franz cell studies.  |  Ingram, RJ., et al. 2002. J Parasitol. 88: 399-402. PMID: 12054019
  3. Environmental fate and effects of dimethicone and cyclotetrasiloxane from personal care applications.  |  Stevens, C. 1998. Int J Cosmet Sci. 20: 296-304. PMID: 18505514
  4. Active agents in common skin care products.  |  Draelos, ZD. 2010. Plast Reconstr Surg. 125: 719-724. PMID: 20124857
  5. Efficacy of premedication with activated Dimethicone or N-acetylcysteine in improving visibility during upper endoscopy.  |  Asl, SM. and Sivandzadeh, GR. 2011. World J Gastroenterol. 17: 4213-7. PMID: 22072853
  6. Compounding with Silicones.  |  Allen, LV. 2015. Int J Pharm Compd. 19: 223-30. PMID: 26714363
  7. Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability.  |  Waqas, MK., et al. 2016. Pak J Pharm Sci. 29: 173-8. PMID: 26826810
  8. Assessment of Efficacy and Irritation of Ingenol Mebutate Gel 0.015% Used With or Without Dimethicone Lotion for Treatment of Actinic Keratosis on the Face.  |  Jim On, SC., et al. 2017. J Drugs Dermatol. 16: 432-436. PMID: 28628678
  9. Lice and Scabies: Treatment Update.  |  Gunning, K., et al. 2019. Am Fam Physician. 99: 635-642. PMID: 31083883
  10. Direct Analysis of Dimethicone in Aqueous Emulsions by Infrared Spectroscopy.  |  Walker, EB. and Naisbitt, CS. 2019. J Cosmet Sci. 70: 209-216. PMID: 31441774
  11. Development and Characterization of A New Dimethicone Nanoemulsion and its Application for Electronic Gastroscopy Examination.  |  Feng, SM., et al. 2020. Int J Nanomedicine. 15: 5405-5416. PMID: 32801696
  12. Effectiveness and tolerability of a squalane and dimethicone-based treatment for head lice.  |  Martínez de Murguía Fernández, L., et al. 2021. Parasitol Res. 120: 1883-1890. PMID: 33797611
  13. Does dimethicone increase the efficacy of antacids in the treatment of reflux oesophagitis?  |  Ogilvie, AL. and Atkinson, M. 1986. J R Soc Med. 79: 584-7. PMID: 3537288
  14. Evaluation in vitro and in vivo of dimethicone transdermal therapeutic systems. Influence of propylene glycol on drug release.  |  Ritschel, WA. and Nayak, PM. 1987. Arzneimittelforschung. 37: 302-6. PMID: 3593444
  15. The effect of activated dimethicone, other antacid constituents, and kaolin on the absorption of propranolol.  |  McElnay, JC., et al. 1982. Experientia. 38: 605-7. PMID: 7095101

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dimethicone, 1 g

sc-498364
1 g
$208.00

Dimethicone, 5 g

sc-498364A
5 g
$306.00

Dimethicone, 25 g

sc-498364B
25 g
$416.00

Dimethicone, 100 g

sc-498364C
100 g
$626.00