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Diisopropyl methylphosphonate (CAS 1445-75-6)

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Alternate Names:
2-[methyl(propan-2-yloxy)phosphoryl]oxypropane
Application:
Diisopropyl methylphosphonate is reacts with esters giving β-keto phosphonates
CAS Number:
1445-75-6
Purity:
≥94%
Molecular Weight:
180.18
Molecular Formula:
C7H17O3P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diisopropyl methylphosphonate (DIMP) is a colorless and odorless chemical compound composed of a methylphosphonate group attached to two isopropyl groups. With a melting point of around -30°C, it is a water-soluble compound with various applications. In scientific research, Diisopropyl methylphosphonate is widely employed as a reagent for chemical synthesis. Moreover, it serves as a key component in the synthesis of other organic compounds like polymers and surfactants. Although the exact mechanism of action of Diisopropyl methylphosphonate is not fully understood, it is known to exhibit both strong nucleophilic and electrophilic properties. These characteristics enable it to readily react with other molecules. Additionally, Diisopropyl methylphosphonate has the ability to form complexes with metal ions, which can act as catalysts in various reactions.


Diisopropyl methylphosphonate (CAS 1445-75-6) References

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  2. Toxicity of diisopropyl methylphosphonate (DIMP) to aquatic organisms.  |  Burton, DT., et al. 2002. Bull Environ Contam Toxicol. 68: 282-9. PMID: 11815800
  3. Two-generation reproductive study in mink fed diisopropyl methylphosphonate (DIMP).  |  Bucci, TJ., et al. 2003. Reprod Toxicol. 17: 327-34. PMID: 12759102
  4. Effect of an environmental contaminant, diisopropyl methylphosphonate, on the blood pressure of the mallard.  |  Jones, RE., et al. 1992. Biomed Environ Sci. 5: 314-20. PMID: 1489525
  5. Dermal penetration of 14C-labeled diisopropyl methylphosphonate in swine.  |  Snodgrass, HL. and Metker, LM. 1992. J Toxicol Environ Health. 36: 367-76. PMID: 1507268
  6. Spectroscopic investigation of the noncovalent association of the nerve agent simulant diisopropyl methylphosphonate (DIMP) with zinc(II) porphyrins.  |  Maza, WA., et al. 2013. J Phys Chem A. 117: 11308-15. PMID: 24093669
  7. Oxidative Destruction of Multilayer Diisopropyl Methylphosphonate Films by O(3P) Atomic Oxygen.  |  Thompson, RS., et al. 2018. J Phys Chem B. 122: 455-463. PMID: 28459150
  8. In vitro human skin permeation and decontamination of diisopropyl methylphosphonate (DIMP) using Dermal Decontamination Gel (DDGel) and Reactive Skin Decontamination Lotion (RSDL) at different timepoints.  |  Cao, Y., et al. 2018. Toxicol Lett. 299: 118-123. PMID: 30282006
  9. Acetylcholinesterase-functionalized two-dimensional photonic crystal for the sensing of G-series nerve agents.  |  Qi, F., et al. 2019. Anal Bioanal Chem. 411: 2577-2585. PMID: 30847569
  10. Follicular pathway role in chemical warfare simulants percutaneous penetration.  |  Elmahdy, A., et al. 2021. J Appl Toxicol. 41: 964-971. PMID: 33030226
  11. Part-per-Trillion Trace Selective Gas Detection Using Frequency Locked Whispering-Gallery Mode Microtoroids.  |  Li, C., et al. 2022. ACS Appl Mater Interfaces. 14: 42430-42440. PMID: 36049126
  12. Surface Tension of Organophosphorus Compounds: Sarin and its Surrogates.  |  Ivanova, EV., et al. 2023. Langmuir. 39: 5569-5578. PMID: 37014998
  13. Toxicologic evaluation of diisopropyl methylphosphonate and dicyclopentadiene in cattle.  |  Cysewski, SJ., et al. 1981. Arch Environ Contam Toxicol. 10: 605-15. PMID: 7305451
  14. Subchronic oral toxicity study of diisopropyl methylphosphonate in mink.  |  Bucci, TJ., et al. 1994. Fundam Appl Toxicol. 22: 220-30. PMID: 8005374

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diisopropyl methylphosphonate, 5 g

sc-268917
5 g
$72.00