Diisononyl Phthalate (CAS 28553-12-0)
CAS Number:
28553-12-0
Molecular Weight:
418.62
Molecular Formula:
C26H42O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Diisononyl Phthalate (DNP) presents as an oily, colorless liquid that emanates a mild ester odor. It is denser than water and is insoluble in water.Diisononyl phthalate is a plasticizer that comprises a mixture of 9-carbon branched dialkyl phthalate isomers. It is able to plasticize a wide array of polyvinylchloride (PVC) products which are prevalently utilized in personal care items and the production of nutritional supplements. As the diisononyl ester of benzene-1,2-dicarboxylic acid, Diisononyl Phthalate operates as a plasticizer and is categorized as both a phthalate ester and a diester. It is thought that Diisononyl Phthalate, like DEHP or other peroxisome proliferators, induces liver effects through a PPARalpha-dependent mechanism.
Diisononyl Phthalate (CAS 28553-12-0) References
- Human biological monitoring of diisononyl phthalate and diisodecyl phthalate: a review. | Saravanabhavan, G. and Murray, J. 2012. J Environ Public Health. 2012: 810501. PMID: 22505951
- Diisononyl phthalate aggravates allergic dermatitis by activation of NF-kB. | Kang, J., et al. 2016. Oncotarget. 7: 85472-85482. PMID: 27863430
- Diisononyl phthalate induces asthma via modulation of Th1/Th2 equilibrium. | Hwang, YH., et al. 2017. Toxicol Lett. 272: 49-59. PMID: 28300662
- Effects of diisononyl phthalate on osteopenia in intact mice. | Hwang, YH., et al. 2017. Toxicol Appl Pharmacol. 334: 120-128. PMID: 28893586
- Exposure to diisononyl phthalate induced an increase in blood pressure through activation of the ACE/ AT1R axis and inhibition of NO production. | Deng, T., et al. 2019. Toxicol Lett. 309: 42-50. PMID: 30940551
- Diisononyl Phthalate Differentially Affects Sirtuin Expression in the HepG2 Cell Line. | Gutiérrez-García, AK., et al. 2019. Chem Res Toxicol. 32: 1863-1870. PMID: 31423773
- Late-life consequences of short-term exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate during adulthood in female mice. | Chiang, C., et al. 2020. Reprod Toxicol. 93: 28-42. PMID: 31904422
- Occupational Exposure of Plastics Workers to Diisononyl Phthalate (DiNP) and Di(2-propylheptyl) Phthalate (DPHP) in Finland. | Porras, SP., et al. 2020. Int J Environ Res Public Health. 17: PMID: 32204423
- Exposure to diisononyl phthalate promotes atopic march by activating of NF-κB and p38 MAPK. | Qin, W., et al. 2020. Toxicol Appl Pharmacol. 395: 114981. PMID: 32240662
- Exposure evaluation of diisononyl phthalate in the adults of Drosophila melanogaster: Potential risks in fertility, lifespan, behavior, and modes of action. | Zhang, Q., et al. 2020. Comp Biochem Physiol C Toxicol Pharmacol. 238: 108847. PMID: 32781294
- Detrimental effects induced by diisononyl phthalate on development and behavior of Drosophila larva and potential mechanisms. | Zhang, Q., et al. 2021. Comp Biochem Physiol C Toxicol Pharmacol. 243: 108967. PMID: 33412299
- Biodegradation of diisononyl phthalate by a consortium of saline soil bacteria: optimisation and kinetic characterisation. | Pereyra-Camacho, MA., et al. 2021. Appl Microbiol Biotechnol. 105: 3369-3380. PMID: 33797572
- Effects of diisononyl phthalate exposure on the oxidative stress and gut microorganisms in earthworms (Eisenia fetida). | Zhang, Y., et al. 2022. Sci Total Environ. 822: 153563. PMID: 35104518
- Exposure to diisononyl phthalate deteriorates the quality of porcine oocytes by inducing the apoptosis. | Wang, R., et al. 2023. Ecotoxicol Environ Saf. 254: 114768. PMID: 36917878
- Long-term exposure to di(2-ethylhexyl) phthalate, diisononyl phthalate, and a mixture of phthalates alters estrous cyclicity and/or impairs gestational index and birth rate in mice. | Laws, MJ., et al. 2023. Toxicol Sci. 193: 48-61. PMID: 36929940
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diisononyl Phthalate, 500 g | sc-489046 | 500 g | $58.00 |