Molecular structure of Diisobutyl phthalate, CAS Number: 84-69-5
Diisobutyl phthalate (CAS 84-69-5)
Alternate Names:
DIBP
CAS Number:
84-69-5
Molecular Weight:
278.34
Molecular Formula:
C16H22O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Diisobutyl phthalate functions as a plasticizer in experimental applications. It acts by increasing the flexibility and durability of various materials, such as polymers and resins, without undergoing significant changes itself. Diisobutyl Phthalate interacts at the molecular level by forming non-covalent bonds with the polymer chains, reducing intermolecular forces and allowing the material to become more pliable. Diisobutyl phthalate achieves this by diffusing into the polymer matrix and creating spaces between the polymer chains, thereby decreasing the glass transition temperature and increasing the material′s flexibility. Diisobutyl Phthalate′s mechanism of action involves enhancing the performance of various materials, which may be useful for experimental purposes in the development of new products and materials.
Diisobutyl phthalate (CAS 84-69-5) References
- Diisobutyl phthalate impairs the androgen-dependent reproductive development of the male rat. | Saillenfait, AM., et al. 2008. Reprod Toxicol. 26: 107-15. PMID: 18706996
- Hazard to the developing male reproductive system from cumulative exposure to phthalate esters--dibutyl phthalate, diisobutyl phthalate, butylbenzyl phthalate, diethylhexyl phthalate, dipentyl phthalate, and diisononyl phthalate. | Benson, R. 2009. Regul Toxicol Pharmacol. 53: 90-101. PMID: 19110024
- Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate. | Hannas, BR., et al. 2011. Toxicol Sci. 123: 206-16. PMID: 21633115
- Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses. | Koch, HM., et al. 2012. Arch Toxicol. 86: 1829-39. PMID: 22820759
- Development and application of simple pharmacokinetic models to study human exposure to di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP). | Lorber, M. and Koch, HM. 2013. Environ Int. 59: 469-77. PMID: 23955327
- Hazards of diisobutyl phthalate (DIBP) exposure: A systematic review of animal toxicology studies. | Yost, EE., et al. 2019. Environ Int. 125: 579-594. PMID: 30591249
- Phthalate exposure and neurodevelopment: A systematic review and meta-analysis of human epidemiological evidence. | Radke, EG., et al. 2020. Environ Int. 137: 105408. PMID: 32045779
- Development of a whole-cell biocatalyst for diisobutyl phthalate degradation by functional display of a carboxylesterase on the surface of Escherichia coli. | Ding, J., et al. 2020. Microb Cell Fact. 19: 114. PMID: 32471417
- The reproductive toxicity and potential mechanisms of combined exposure to dibutyl phthalate and diisobutyl phthalate in male zebrafish (Danio rerio). | Chen, H., et al. 2020. Chemosphere. 258: 127238. PMID: 32563064
- Toxicokinetics of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate, in rats: UPLC-ESI-MS/MS method development for the simultaneous determination of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate, in rat plasma, urine, feces, and 11 various tissues collected from a toxicokinetic study. | Jeong, SH., et al. 2020. Food Chem Toxicol. 145: 111747. PMID: 32926938
- Transcriptomic responses predict the toxic effect of parental co-exposure to dibutyl phthalate and diisobutyl phthalate on the early development of zebrafish offspring. | Chen, H., et al. 2021. Aquat Toxicol. 235: 105838. PMID: 33910148
- Toxicokinetic assessment of inhalatory absorption of Diisobutyl phthalate (DiBP) using a novel thermal desorption-GC-MS method to determine phthalate diesters in blood plasma. | Palacios-Arreola, MI., et al. 2022. Environ Toxicol Pharmacol. 90: 103813. PMID: 35033683
- Development of ecological risk assessment for Diisobutyl phthalate and di-n-octyl phthalate in surface water of China based on species sensitivity distribution model. | Huan-Yu, T., et al. 2022. Chemosphere. 307: 135932. PMID: 35940414
- Eucalyptol relieves the toxicity of diisobutyl phthalate in Ctenopharyngodon idellus kidney cells through Keap1/Nrf2/HO-1 pathway: Apoptosis-autophagy crosstalk and immunoregulation. | Liu, H., et al. 2022. Fish Shellfish Immunol. 130: 490-500. PMID: 36162772
- Extreme environmental doses of diisobutyl phthalate exposure induce oxidative stress and DNA damage in earthworms (Eisenia fetida): Evidence at the biochemical and molecular levels. | Yao, X., et al. 2023. J Environ Manage. 331: 117321. PMID: 36657203
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diisobutyl phthalate, 100 g | sc-353228 | 100 g | $56.00 | |||
Diisobutyl phthalate, 500 g | sc-353228A | 500 g | $220.00 |