Molecular structure of Diiodoacetic Acid
Diiodoacetic Acid (CAS 598-89-0)
Alternate Names:
2,2-Diiodoacetic Acid
Application:
Diiodoacetic Acid is a byproduct formed in waters treated with chlorine and iodine
CAS Number:
598-89-0
Molecular Weight:
311.85
Molecular Formula:
C2H2I2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Diiodoacetic acid (DIDA) used in research to probe the structure and functionality of enzymes, and to understand the reaction mechanisms of various substances. Additionally, it plays a role in studies focused on oxidative stress and the impacts of environmental contaminants. Its chemical activity allows it to participate in oxidation-reduction reactions, affecting proteins, carbohydrates, and lipids. Diiodoacetic Acid can catalyze the oxidation of other molecules and also function as a scavenger of free radicals.
Diiodoacetic Acid (CAS 598-89-0) References
- Reduction of MTT by aqueous herbal extracts in the absence of cells. | Shoemaker, M., et al. 2004. J Ethnopharmacol. 93: 381-4. PMID: 15234781
- Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures. | Rogel, A., et al. 2005. Neurosci Lett. 373: 218-21. PMID: 15619546
- Localization and quantitation of free sulfhydryl in recombinant monoclonal antibodies by differential labeling with 12C and 13C iodoacetic acid and LC-MS analysis. | Xiang, T., et al. 2009. Anal Chem. 81: 8101-8. PMID: 19722496
- Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products. | Plewa, MJ., et al. 2010. Environ Mol Mutagen. 51: 871-8. PMID: 20839218
- Anatomical evidence of photoreceptor degeneration induced by iodoacetic acid in the porcine eye. | Scott, PA., et al. 2011. Exp Eye Res. 93: 513-27. PMID: 21740901
- Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. | Wei, X., et al. 2013. Environ Sci Technol. 47: 5913-20. PMID: 23641915
- Alterations of ultrastructure and elemental composition in cultured neonatal rat cardiac myocytes after metabolic inhibition with iodoacetic acid. | Buja, LM., et al. 1985. Lab Invest. 53: 397-412. PMID: 2413276
- The effects of iodoacetic acid on the mouse retina. | Rösch, S., et al. 2015. Graefes Arch Clin Exp Ophthalmol. 253: 25-35. PMID: 24827634
- Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. | Wang, S. and Kaltashov, IA. 2015. J Am Soc Mass Spectrom. 26: 800-7. PMID: 25716754
- Formation of iodo-trihalomethanes, iodo-acetic acids, and iodo-acetamides during chloramination of iodide-containing waters: Factors influencing formation and reaction pathways. | Liu, S., et al. 2017. J Hazard Mater. 321: 28-36. PMID: 27607930
- Iodoacetic acid inhibits follicle growth and alters expression of genes that regulate apoptosis, the cell cycle, estrogen receptors, and ovarian steroidogenesis in mouse ovarian follicles. | Gonsioroski, A., et al. 2020. Reprod Toxicol. 91: 101-108. PMID: 31693920
- Androgenic and Teratogenic Effects of Iodoacetic Acid Drinking Water Disinfection Byproduct in Vitro and in Vivo. | Long, K., et al. 2021. Environ Sci Technol. 55: 3827-3835. PMID: 33646749
- Iodoacetic acid affects estrous cyclicity, ovarian gene expression, and hormone levels in mice†. | Gonsioroski, A., et al. 2021. Biol Reprod. 105: 1030-1042. PMID: 34086879
- Iodoacetic Acid, a Water Disinfection Byproduct, Disrupts Hypothalamic, and Pituitary Reproductive Regulatory Factors and Induces Toxicity in the Female Pituitary. | Gonzalez, RVL., et al. 2021. Toxicol Sci. 184: 46-56. PMID: 34453833
- Biochars intended for water filtration: A comparative study with activated carbons of their physicochemical properties and removal efficiency towards neutral and anionic organic pollutants. | Castiglioni, M., et al. 2022. Chemosphere. 288: 132538. PMID: 34648788
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diiodoacetic Acid, 100 mg | sc-394115 | 100 mg | $404.00 |