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Dihydrosafrole (CAS 94-58-6)

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Alternate Names:
5-Propyl-1,3-benzodioxole; 1,2-(Methylenedioxy)-4-propyl-benzene
CAS Number:
94-58-6
Molecular Weight:
164.20
Molecular Formula:
C10H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dihydrosafrole functions as a precursor in the synthesis of various organic compounds. Its mechanism of action involves participating in organic reactions, such as oxidation, reduction, and condensation, to form complex molecular structures. Dihydrosafrole interacts with other reagents to facilitate the formation of new chemical bonds and the creation of diverse chemical products. Its functional role lies in its ability to undergo specific chemical transformations, contributing to the synthesis of a wide range of organic compounds. At the molecular level, dihydrosafrole engages in chemical reactions that lead to the formation of complex molecular structures, serving as a building block for the creation of various chemical products.


Dihydrosafrole (CAS 94-58-6) References

  1. [Ethylene bonds and toxicity; studies on dihydroanethole p-propylanisole) and on dihydrosafrole (1,2-methdenedioxy-4-propylbenzene)].  |  CAUJOLLE, F. and MEYNIER, D. 1958. C R Hebd Seances Acad Sci. 247: 1916-7. PMID: 13609062
  2. Larvicidal and structure-activity studies of natural phenylpropanoids and their semisynthetic derivatives against the tobacco armyworm Spodoptera litura (Fab.) (Lepidoptera: Noctuidae).  |  Bhardwaj, A., et al. 2010. Chem Biodivers. 7: 168-77. PMID: 20087983
  3. Sonoelectrochemical hydrogenation of safrole: A reactor design, statistical analysis and computational fluid dynamic approach.  |  da Paz, JA., et al. 2020. Ultrason Sonochem. 63: 104949. PMID: 31952006
  4. Inhibition of cytochrome P-450c-mediated benzo[a]pyrene hydroxylase and ethoxyresorufin O-deethylase by dihydrosafrole.  |  Kao, LR. and Wilkinson, CF. 1987. Xenobiotica. 17: 793-805. PMID: 3660849
  5. Spectral and inhibitory interactions of methylenedioxyphenyl and related compounds with purified isozymes of cytochrome P-450.  |  Marcus, CB., et al. 1985. Xenobiotica. 15: 351-62. PMID: 4024670
  6. Neoplasms of the forestomach in mice ingesting dihydrosafrole.  |  Reuber, MD. 1979. Digestion. 19: 42-7. PMID: 456767
  7. Thin-layer chromatography of rat bile and urine following intravenous administration of safrole, isosafrole, and dihydrosafrole.  |  Fishbein, L., et al. 1967. J Chromatogr. 29: 267-73. PMID: 6058212
  8. Induction and suppression of N-nitrosomethylbenzylamine activation by microsomes from rat liver and esophagus.  |  Mehta, R., et al. 1984. J Natl Cancer Inst. 72: 1443-7. PMID: 6587161
  9. Effects of dihydrosafrole on cytochromes P-450 and drug oxidation in hepatic microsomes from control and induced rats.  |  Murray, M., et al. 1983. Toxicol Appl Pharmacol. 68: 66-76. PMID: 6845376
  10. Metabolism of isosafrole and dihydrosafrole in the rat.  |  Klungsøyr, J. and Scheline, RR. 1982. Biomed Mass Spectrom. 9: 323-9. PMID: 7126764
  11. Determination of safrole, dihydrosafrole, and chloromethyldihydrosafrole in piperonyl butoxide by high-performance liquid chromatography.  |  Schreiber-Deturmeny, EM., et al. 1993. J Pharm Sci. 82: 813-6. PMID: 8377120
  12. The prevention of CCl4-induced liver necrosis in mice by naturally occurring methylenedioxybenzenes.  |  Zhao, ZS. and O'Brien, PJ. 1996. Toxicol Appl Pharmacol. 140: 411-21. PMID: 8887459
  13. Liquid chromatographic determination of safrole in sassafras-derived herbal products.  |  Carlson, M. and Thompson, RD. 1997. J AOAC Int. 80: 1023-8. PMID: 9325580

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dihydrosafrole, 25 mg

sc-498541
25 mg
$388.00