Molecular structure of Dihydroergotoxine mesylate, CAS Number: 8067-24-1
Dihydroergotoxine mesylate (CAS 8067-24-1)
Application:
Dihydroergotoxine mesylate is binds with high affinity to GABAA receptor
CAS Number:
8067-24-1
Molecular Weight:
1190.70 (approximate)
Molecular Formula:
C33H45N5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Binds with high affinity to GABAA receptor Cl- channel. Interacts with central dopaminergic, serotonergic and adrenergic (a1) receptors. Exhibits antirproliferative activity in vitro. Displays cognition-enhancing, anticonvulsant and sedative activity in vivo. Active orally.
Dihydroergotoxine mesylate (CAS 8067-24-1) References
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- Influence of dihydroergotoxine, bromocriptine, and ergotamine on penile erection in Wistar rats. | Radosavljevic, M., et al. 2012. J Androl. 33: 866-71. PMID: 22441761
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- [Effects of Tongluo Xingnao effervescent tablets on blood rheology, iNOS, VEGF and LDH-5 in MID rats]. | Ren, XY., et al. 2016. Zhongguo Zhong Yao Za Zhi. 41: 1119-1123. PMID: 28875680
- Transition from androgenic to neurosteroidal action of 5α-androstane-3α, 17β-diol through the type A γ-aminobutyric acid receptor in prostate cancer progression. | Xia, D., et al. 2018. J Steroid Biochem Mol Biol. 178: 89-98. PMID: 29155210
- Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation. | Zimmermann, S., et al. 2019. Front Microbiol. 10: 2762. PMID: 31849901
- Bungeanum Improves Cognitive Dysfunction and Neurological Deficits in D-Galactose-Induced Aging Mice via Activating PI3K/Akt/Nrf2 Signaling Pathway. | Zhao, M., et al. 2020. Front Pharmacol. 11: 71. PMID: 32158388
- Overproduction of medicinal ergot alkaloids based on a fungal platform. | Yao, Y., et al. 2022. Metab Eng. 69: 198-208. PMID: 34902590
Substrate of:
GABA Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dihydroergotoxine mesylate, 100 mg | sc-203921 | 100 mg | $109.00 |