Dihydroergotamine (+)-tartrate salt is a vasoconstrictor and vascular serotonin receptor activator. Dihydroergotamine (+)-tartrate salt also exhibits α-adrenergic and dopamine D2 receptor partial activator activity.
Lesage, A.S., et al., Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines. Br. J. Pharmacol. 123, 1655, (1998) Glusa, E., and Roos, A., Endothelial 5-HT receptors mediate relaxation of porcine pulmonary arteries in response to ergotamine and dihydroergotamine. Br. J. Pharmacol. 119, 330-334, (1996) Villalon, C.M., et al., Canine external carotid vasoconstriction to methysergide, ergotamine and dihydroergotamine: role of 5-HT1B/1D receptors and alpha2-adrenoceptors. Br. J. Pharmacol. 126, 585, (1999)
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