Date published: 2026-4-5

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Dihydrochlamydocin

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Application:
Dihydrochlamydocin is a biologically active peptide that acts as an HDAC inhibitor
Molecular Weight:
528.64
Molecular Formula:
C28H40N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dihydrochlamydocin is a bioactive secondary metabolite produced by various strains of Streptomyces bacteria. It belongs to the class of cyclic tetrapeptides and exhibits potent antimicrobial properties against a wide range of pathogenic bacteria and fungi. The mechanism of action of dihydrochlamydocin involves disruption of microbial cell membrane integrity, leading to leakage of cellular contents and eventual cell death. In research, dihydrochlamydocin has been extensively studied for its antimicrobial activity and its potential as a lead compound for the development of novel antimicrobial agents. Researchers have investigated the structure-activity relationships of dihydrochlamydocin derivatives to enhance its antimicrobial efficacy and selectivity. Furthermore, dihydrochlamydocin has been utilized as a tool in microbiology and molecular biology studies to explain the mechanisms underlying microbial membrane permeabilization and to identify potential molecular targets within microbial cells. Overall, dihydrochlamydocin holds promise as a valuable research tool for studying microbial biology and for the development of new strategies to combat microbial infections and drug-resistant pathogens.


Dihydrochlamydocin References

  1. Conformation of the cyclic tetrapeptide dihydrochlamydocin. Iabu-L-Phe D-Pro-LX, and experimental values for 3 leads to 1 intramolecular hydrogen bonds by X-ray diffraction.  |  Flippen, JL. and Karle, IL. 1976. Biopolymers. 15: 1081-92. PMID: 1268315
  2. Host cell-specific metabolism of linoleic acid controls Toxoplasma gondii growth in cell culture.  |  Hryckowian, ND., et al. 2024. bioRxiv.. PMID: 38562845
  3. The backbone and side chain conformations of the cyclic tetrapeptide HC-toxin.  |  Mascagni, P., et al. 1983. Biochem Biophys Res Commun. 113: 10-7. PMID: 6860326

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dihydrochlamydocin, 250 µg

sc-396552
250 µg
$90.00