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Dihydroavermectin B1a (CAS 70161-11-4)

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Alternate Names:
Ivermectin; Ivermectin B1a
Application:
Dihydroavermectin B1a is an anthelmintic that binds to glutamate-gated chloride channels
CAS Number:
70161-11-4
Purity:
≥85%
Molecular Weight:
875.1
Molecular Formula:
C48H74O14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dihydroavermectin B1a is a chemical compound that functions as an inhibitor of neurotransmission in nematodes and arthropods. It acts by binding to glutamate-gated chloride channels in the nerve and muscle cells of these organisms, leading to an increase in the permeability of the cell membrane to chloride ions. This results in hyperpolarization of the nerve or muscle cells, leading to paralysis and death of the targeted parasites. The compound′s mechanism of action involves disrupting the normal functioning of the nervous system in these organisms, ultimately leading to their immobilization and elimination.


Dihydroavermectin B1a (CAS 70161-11-4) References

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  5. Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.  |  Bowman, JW., et al. 1991. Comp Biochem Physiol C Comp Pharmacol Toxicol. 99: 333-40. PMID: 1685403
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  13. Anthelmintic efficacy of avermectin B1a and dihydroavermectin B1a against ovine gastrointestinal nematodes in 1977.  |  Todd, KS., et al. 1984. Am J Vet Res. 45: 976-7. PMID: 6547280
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dihydroavermectin B1a, 5 mg

sc-202138
5 mg
$327.00