Molecular structure of Dihomo-γ-linolenylethanolamide, CAS Number: 150314-34-4
Dihomo-γ-linolenylethanolamide (CAS 150314-34-4)
Application:
Dihomo-γ-linolenylethanolamide is a CB1 and CB2 agonist and adenylyl cyclase inhibitor
CAS Number:
150314-34-4
Molecular Weight:
349.6
Molecular Formula:
C22H39NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
Dihomo-γ-linolenylethanolamide is an endocannabinoid. Binds to recombinant human CB1 (Ki = 857 nM) and CB2 receptor (Ki = 598nM). Also inhibits adenylyl cyclase (IC50 =109 nM).
Dihomo-γ-linolenylethanolamide (CAS 150314-34-4) References
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- Nonpsychotropic cannabinoid receptors regulate microglial cell migration. | Walter, L., et al. 2003. J Neurosci. 23: 1398-405. PMID: 12598628
- Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. | Felder, CC., et al. 1995. Mol Pharmacol. 48: 443-50. PMID: 7565624
- Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia. | Pertwee, R., et al. 1994. Eur J Pharmacol. 259: 115-20. PMID: 7957604
- Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. | Felder, CC., et al. 1993. Proc Natl Acad Sci U S A. 90: 7656-60. PMID: 8395053
- Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. | Hanus, L., et al. 1993. J Med Chem. 36: 3032-4. PMID: 8411021
- Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. | Barg, J., et al. 1995. Eur J Pharmacol. 287: 145-52. PMID: 8749028
- Endogenous cannabinoid ligands--chemical and biological studies. | Mechoulam, R., et al. 1996. J Lipid Mediat Cell Signal. 14: 45-9. PMID: 8906544
- Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. | Jarrahian, A. and Hillard, CJ. 1997. Prostaglandins Leukot Essent Fatty Acids. 57: 551-4. PMID: 9431821
Inhibitor of:
Adenylyl Cyclase.Activator of:
CB1, and CB2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dihomo-γ-linolenylethanolamide, 5 mg | sc-202137 | 5 mg | $55.00 |