Molecular structure of Difluoromethylenediphosphonic Acid, CAS Number: 10596-32-4
Difluoromethylenediphosphonic Acid (CAS 10596-32-4)
Application:
Difluoromethylenediphosphonic Acid is a phosphonic acid derivative
CAS Number:
10596-32-4
Molecular Weight:
211.98
Molecular Formula:
CH4F2O6P2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Difluoromethylenediphosphonic Acid is a phosphonic acid derivative for development of biologically active compounds. Difluoromethylene diphosphonate, a synthetic organophosphate compound, finds extensive utility in scientific research. Its applications in scientific research encompass diverse areas, including biochemical and physiological investigations, as well as compound synthesis. Notably, it exhibits inhibitory properties towards enzymes such as protein kinases, phospholipases, and proteases. Moreover, it influences the transport of molecules across cell membranes and modulates membrane permeability. Additionally, it may act to impact the activity of specific ion channels.
Difluoromethylenediphosphonic Acid (CAS 10596-32-4) References
- Synthesis of AZT 5'-triphosphate mimics and their inhibitory effects on HIV-1 reverse transcriptase. | Wang, G., et al. 2004. J Med Chem. 47: 6902-13. PMID: 15615539
- Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. | Ko, H., et al. 2008. Bioorg Med Chem. 16: 6319-32. PMID: 18514530
- Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold. | Erixon, KM., et al. 2008. Org Biomol Chem. 6: 3561-72. PMID: 19082157
- Uptake of a fluorinated bisphosphonate by cultured bones. | Rowe, DJ. and Etre, LA. 1988. Bone. 9: 297-301. PMID: 2974292
- Pharmacological effects of isopolar phosphonate analogues of ATP on P2-purinoceptors in guinea-pig taenia coli and urinary bladder. | Cusack, NJ., et al. 1987. Br J Pharmacol. 90: 791-5. PMID: 3580709
- A convenient strategy for replacement of the anomeric hydroxyl group by difluoromethyl functionality in carbohydrate derivatives | JS Houlton, WB Motherwell, BC Ross, MJ Tozer… - Tetrahedron, 1993 - Elsevier. September 1993,. Tetrahedron. Volume 49, Issue 36, 3: Pages 8087-8106.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Difluoromethylenediphosphonic Acid, 2.5 mg | sc-211329 | 2.5 mg | $400.00 |