Diflubenzuron (CAS 35367-38-5)
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Diflubenzuron is a benzoyl-urea insecticide, found to be a potent inhibitor of melanosome synthesis in mouse melanoma cells. Diflubenzuron has also been shown to inhibit TCDD-induced CYP1A1 expression in HepG2 cells.Diflubenzuron is also known as dimilin or difluron and falls into the category of n-benzoyl-n′-phenylureas, characterized by a phenyl group substituting the acyl group. In its chemical structure, a hydrogen atom on one nitrogen is replaced by a 4-chlorophenyl group, while the other nitrogen has a 2,6-difluorobenzoyl group instead of a hydrogen atom. It is primarily utilized as a selective insecticide.Within the cellular context, diflubenzuron tends to accumulate in the membrane due to its predicted logP properties. It can be biosynthesized from 1,3-difluorobenzene. It′s essential to handle diflubenzuron with care, as it is considered a potentially toxic compound with the ability to disrupt insect growth and development effectively.
Diflubenzuron (CAS 35367-38-5) References
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- Effectiveness of Diflubenzuron in the control of houseflies. | Tilak, R., et al. 2010. J Vector Borne Dis. 47: 97-102. PMID: 20539047
- Metabolism of Diflubenzuron in Lizard (Eremias argus) and Comparative Toxicity of Diflubenzuron and Its Metabolite. | Wang, H., et al. 2018. J Agric Food Chem. 66: 11640-11646. PMID: 30346759
- Susceptibility and alterations by diflubenzuron in larvae of Aedes aegypti. | Montaño-Reyes, A., et al. 2019. Arch Insect Biochem Physiol. 102: e21604. PMID: 31328823
- Detection of diflubenzuron and pyrethroid resistance mutations in Culex pipiens from Muğla, Turkey. | Guz, N., et al. 2020. Acta Trop. 203: 105294. PMID: 31836282
- Impact of Diflubenzuron on Bombus impatiens (Hymenoptera: Apidae) Microcolony Development. | Camp, AA., et al. 2020. Environ Entomol. 49: 203-210. PMID: 31858127
- Effect of diflubenzuron on the chitin biosynthesis pathway in Conopomorpha sinensis eggs. | Yao, Q., et al. 2021. Insect Sci. 28: 1061-1075. PMID: 32686293
- Diflubenzuron leads to apoptotic cell death through ROS generation and mitochondrial dysfunction in bovine mammary epithelial cells. | Lee, W., et al. 2021. Pestic Biochem Physiol. 177: 104893. PMID: 34301355
- Effects of Temephos (Abate®), Spinosad (Natular®), and Diflubenzuron on the Survival of Cyclopoid Copepods. | Grunert, R., et al. 2022. Am J Trop Med Hyg. 106: 818-822. PMID: 35073509
- Risk assessment of resistance to diflubenzuron in Musca domestica: Realized heritability and cross-resistance to fourteen insecticides from different classes. | Hafez, AM. 2022. PLoS One. 17: e0268261. PMID: 35560149
- Diflubenzuron Induces Cardiotoxicity in Zebrafish Embryos. | Han, X., et al. 2022. Int J Mol Sci. 23: PMID: 36233243
- Influence of Monensin and Diflubenzuron on the Control of Immature Horn Fly and House Fly (Diptera: Muscidae) and Chemical Composition of Cattle Feces. | Sanchez-Sandoval, UA., et al. 2023. J Med Entomol. 60: 417-421. PMID: 36539325
- Cuticle Modifications and Over-Expression of the Chitin-Synthase Gene in Diflubenzuron-Resistant Phenotype. | Lucchesi, V., et al. 2022. Insects. 13: PMID: 36555019
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diflubenzuron, 10 g | sc-204722 | 10 g | $245.00 | |||
Diflubenzuron, 25 g | sc-204722A | 25 g | $459.00 |