Diflubenzuron is a benzoyl-urea insecticide, found to be a potent inhibitor of melanosome synthesis in mouse melanoma cells. Diflubenzuron has also been shown to inhibit TCDD-induced CYP1A1 expression in HepG2 cells.
Norman JO, Meola SM. Antimicrob Agents Ch. 23:313-6 (1983). Ledirac N, Delescluse C, Lesca P et al. Toxicol Appl Pharm. 164:273-9 (2000).
Soluble in methanol, DMSO, acetone (6.5 mg/ml at 20° C), and ethanol. Insoluble in water.
Store at room temperature
210-232° C @95%pure
~1.5 g/cm3 (Predicted)
n20D 1.62 (Predicted)
CCRF-CEM: IC50 >20 ug/ml (human)
pKa: 8.78 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Suman et al (PubMed ID 23860181) found thatSuman et al (PubMed ID 23860181) found that the chitin synthesis inhibitor, diflubenzuron, caused changes in the egg shell morphology and abnormal egg hatching from the side of the egg wall instead of operculum of Culex mosquitoes. -SCBT Publication Review
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