Date published: 2026-4-25

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Diethylamino-acetic acid (CAS 1606-01-5)

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Alternate Names:
N,N-Diethylglycine
CAS Number:
1606-01-5
Molecular Weight:
131.18
Molecular Formula:
C6H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diethylamino-acetic acid, also known as N,N-Diethylglycine (DEG), an amino acid derivative, is synthesized by reacting glycine and ethyl bromide in the presence of sodium hydroxide and a base. It finds application in enzyme kinetics and the study of enzyme inhibitors. Diethylamino-acetic acid acts as an inhibitor for several enzymes, such as glutathione-S-transferase, cytosolic and mitochondrial aldehyde dehydrogenase, and monoamine oxidase. It also acts as a GABA receptor agonist, elevating GABA levels in the brain while reducing glutamate levels. Furthermore, Diethylamino-acetic acid exhibits anti-inflammatory, antioxidant, and anti-apoptotic effects.


Diethylamino-acetic acid (CAS 1606-01-5) References

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  2. Enhanced analgesic effects of propacetamol and tramadol combination in rats and mice.  |  Zhang, Y., et al. 2011. Biol Pharm Bull. 34: 349-53. PMID: 21372383
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  5. Novel Carbonyl Analogs of Tamoxifen: Design, Synthesis, and Biological Evaluation.  |  Kasiotis, KM., et al. 2017. Front Chem. 5: 71. PMID: 29018796
  6. The Efficacy of 4% Articaine Versus 2% Lidocaine in Inducing Palatal Anesthesia for Tooth Extraction in Different Maxillary Regions.  |  Gholami, M., et al. 2021. J Oral Maxillofac Surg. 79: 1643-1649. PMID: 33757745

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diethylamino-acetic acid, 500 mg

sc-326819
500 mg
$275.00