Diethylamine (CAS 109-89-7)

Diethylamine (DEA), recognized by its chemical formula (C2H5)2NH, is classified as an organic base and a weak σ-donor ligand. Its primary function involves serving as a bond-breaking agent in a novel Enzyme-Linked Immunosorbent Assay (ELISA) designed to measure the avidity index (AI) of Immunoglobulin G-anti-pertussis toxin (IgG-anti-PT) antibodies.Physically, diethylamine presents as a clear, colorless liquid that emits an odor reminiscent of ammonia. Its vapors tend to be denser than the surrounding air, and during combustion, it produces toxic oxides of nitrogen.Diethylamine falls under the category of dialkylamines, which are organic compounds featuring a dialkylamine group characterized by two alkyl groups attached to the amino nitrogen. This compound is predominantly liquid, soluble in water, and exhibits strong basic properties, as evidenced by its low pKa value. Additionally, diethylamine can be chemically transformed into N-(trimethylsilyl)diethylamine. Diethylamine is a secondary aliphatic amine with two ethyl substituents on its nitrogen atoms, and it functions as the conjugate base of diethylammonium. Its diverse properties and chemical characteristics make it a valuable component in various scientific applications, including ELISA assays.