Diethyl (Boc-amino)malonate (CAS 102831-44-7)
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Diethyl (Boc-amino)malonate is a versatile reagent used in organic synthesis, particularly in the preparation of amino acid derivatives and peptides. The Boc (tert-butoxycarbonyl) group attached to the amino function serves as a protective group, allowing the amino moiety to remain unreactive during certain reactions. This feature is essential when sequentially building peptide chains, as it prevents unwanted side reactions. Researchers utilize diethyl (Boc-amino)malonate for the synthesis of non-natural amino acids, which are key to studying protein structure and function, as well as to produce specialized peptides with potential industrial and biotechnological applications. In addition, this compound is instrumental in the preparation of gamma-aminobutyric acid (GABA) analogs, contributing to research focused on neurotransmission.
Diethyl (Boc-amino)malonate (CAS 102831-44-7) References
- 2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors. | Golebiowski, A., et al. 2013. Bioorg Med Chem Lett. 23: 2027-30. PMID: 23453840
- Cyclic tetrapeptides with -SS- bridging between amino acid side chains for potent histone deacetylases' inhibition. | Arai, T., et al. 2013. Amino Acids. 45: 835-43. PMID: 23754115
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diethyl (Boc-amino)malonate, 25 ml | sc-207569 | 25 ml | $291.00 |