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Diethoxyacetonitrile (CAS 6136-93-2)

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Application:
Diethoxyacetonitrile is a useful biochemical for synthesis of many chemicals
CAS Number:
6136-93-2
Purity:
97%
Molecular Weight:
129.16
Molecular Formula:
C6H11NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diethoxyacetonitrile is a chemical used for synthesis. With this chemical you can synthesize methyl 5-diethoxymethylimidazole-4-carboxylate by anionic cycloaddition of methyl isocyanoacetate to diethoxyacetonitrile. You can also synthesize ketoacetal, by Houben-Hoesch reaction of diethoxyacetonitrile with 1,2,4-trimethoxybenzene.


Diethoxyacetonitrile (CAS 6136-93-2) References

  1. A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: inhibitory activity against the West Nile virus NTPase/helicase.  |  Ujjinamatada, RK., et al. 2005. Nucleosides Nucleotides Nucleic Acids. 24: 1775-88. PMID: 16438047
  2. Expedient synthesis of N-methyl tubulysin analogues with high cytotoxicity.  |  Patterson, AW., et al. 2008. J Org Chem. 73: 4362-9. PMID: 18479168
  3. An improved synthesis of pyridine-thiazole cores of thiopeptide antibiotics.  |  Aulakh, VS. and Ciufolini, MA. 2009. J Org Chem. 74: 5750-3. PMID: 19572592
  4. Total synthesis and complete structural assignment of thiocillin I.  |  Aulakh, VS. and Ciufolini, MA. 2011. J Am Chem Soc. 133: 5900-4. PMID: 21446660
  5. A trans-AB-bacteriochlorin building block.  |  Mass, O. and Lindsey, JS. 2011. J Org Chem. 76: 9478-87. PMID: 22035424
  6. Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D.  |  Turner, CD. and Ciufolini, MA. 2011. Beilstein J Org Chem. 7: 1475-85. PMID: 22238520
  7. Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor.  |  Miller, DC., et al. 2022. J Med Chem. 65: 6513-6540. PMID: 35468293
  8. Synthesis, crystal structure, and magnetic properties of 5-methyl-l,2,4-triazole-nitronyl nitroxide: A one-dimensional compound with unusually large ferromagnetic intermolecular interactions  |  Prof. Olivier Kahn, Dr. Andreas Lang, Dr. Yu Pei, Dr. Lahcène Ouahab. January 1996. Advanced Materials. Volume8, Issue1: Pages 60-62.
  9. Easy Access to 2-Alkyl and 2-Arylthiazolines Using a Modified Heteropolyacid Catalysis: Application to the Synthesis of Bacillamide A  |  F. Fache,F. Cros,O. Piva &F. Lefebvre. 2012 -. Synthetic Communications An International Journal for Rapid Communication of Synthetic Organic Chemistry. Volume 42, Issue 14: Pages 2098-2109.
  10. Development of an Efficient, Scalable Route for the Preparation of a Novel Insulin-Like Growth Factor-1 Receptor Modulator  |  CH Vinod Kumar*†, Santosh Kavitake†, Sythana Suresh Kumar†, Philip Cornwall‡, Mithun Ashok†, Sagar Bhagat†, Sulur G. Manjunatha†, and Sudhir Nambiar†. 2012. org. Process Res. Dev.,. 16, 8,: 1416–1421.
  11. Determination of Methyldibromoglutaronitrile (MDBGN) in Skin Care Products by Gaschromatography-Mass Spectrometry Employing an Enhanced Matrix Removal (EMR) Lipid Clean-Up  |  Fiorenza Farè, Michele Dei Cas, Sebastiano Arnoldi, Eleonora Casagni, Giacomo Luca Visconti, Giulia Parnisari, Cristiano Bolchi, Marco Pallavicini, Veniero Gambaro, Gabriella Roda. April 2018. European Journal of Lipid Science and Technology. Volume120, Issue4: 1700525.
  12. Synthesis of methyl sulfomycinate, sulfomycinic amide and sulfomycinine, degradation products of the sulfomycin thiopeptide antibiotics  |  Mark C. Bagley, Christian Glover. 2 January 2006,. Tetrahedron. Volume 62, Issue 1,: Pages 66-72.
  13. Synthesis, solution ESR spectra, and solid-state magnetic property of thieno[3,4-d]imidazol-2-yl nitronyl nitroxide  |  Hideaki Nagashima, Hidenari Inoue, Naoki Yoshioka. 15 July 2003,. Polyhedron. Volume 22, Issues 14–17,: Pages 1823-1827.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diethoxyacetonitrile, 5 g

sc-234625
5 g
$67.00