Date published: 2025-10-15

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Didodecyldimethylammonium bromide (CAS 3282-73-3)

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Alternate Names:
Dimethyldidodecylammonium bromide
Application:
Didodecyldimethylammonium bromide is a phase transfer catalyst
CAS Number:
3282-73-3
Purity:
≥98%
Molecular Weight:
462.63
Molecular Formula:
C26H56N•Br
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Didodecyldimethylammonium bromide is a quaternary ammonium compound that functions as a cationic surfactant in experimental applications. Its mode of action involves disrupting the cell membranes of microorganisms, leading to their lysis and subsequent death. This disruption occurs through the interaction of the positively charged quaternary ammonium group with the negatively charged components of the microbial cell membrane, resulting in destabilization and permeabilization. As a result, Didodecyldimethylammonium bromide exhibits antimicrobial properties, making it useful for its ability to inhibit the growth and proliferation of various microorganisms in research and development applications. Its surfactant properties also allow it to be used for the solubilization and dispersion of hydrophobic compounds in aqueous solutions, further expanding its functional role in experimental applications.


Didodecyldimethylammonium bromide (CAS 3282-73-3) References

  1. XRD, TEM, and thermal analysis of Arizona Ca-montmorillonites modified with didodecyldimethylammonium bromide.  |  Sun, Z., et al. 2013. J Colloid Interface Sci. 408: 75-81. PMID: 23932082
  2. The critical role of didodecyldimethylammonium bromide on physico-chemical, technological and biological properties of NLC.  |  Carbone, C., et al. 2014. Colloids Surf B Biointerfaces. 121: 1-10. PMID: 24929522
  3. Rational design of didodecyldimethylammonium bromide-based nanoassemblies for gene delivery.  |  Jin, Y., et al. 2015. Colloids Surf B Biointerfaces. 126: 257-64. PMID: 25576809
  4. New Perspective in the Formulation and Characterization of Didodecyldimethylammonium Bromide (DMAB) Stabilized Poly(Lactic-co-Glycolic Acid) (PLGA) Nanoparticles.  |  Gossmann, R., et al. 2015. PLoS One. 10: e0127532. PMID: 26147338
  5. Revealing the potential of Didodecyldimethylammonium bromide as efficient scaffold for fabrication of nano liquid crystalline structures.  |  Kanwar, R., et al. 2016. Chem Phys Lipids. 196: 61-8. PMID: 26896840
  6. A comparison of didodecyldimethylammonium bromide adsorbed at mica/water and silica/water interfaces using neutron reflection.  |  Griffin, LR., et al. 2016. J Colloid Interface Sci. 478: 365-73. PMID: 27318715
  7. Removal and degradation of β-lactam antibiotics in water using didodecyldimethylammonium bromide-modified montmorillonite organoclay.  |  Saitoh, T. and Shibayama, T. 2016. J Hazard Mater. 317: 677-685. PMID: 27339949
  8. Gelling Lamellar Phases of the Binary System Water-Didodecyldimethylammonium Bromide with an Organogelator.  |  Koitani, S., et al. 2017. Langmuir. 33: 12171-12179. PMID: 29028344
  9. Effects of the equimolarly mixed cationic-nonionic surfactants of didodecyldimethylammonium bromide and polyoxyethylene sorbitan monooleate 80 on serum proteins-spectroscopic study.  |  Qiao, H., et al. 2018. J Photochem Photobiol B. 187: 151-161. PMID: 30145466
  10. Didodecyldimethylammonium Bromide Role in Anchoring Gold Nanoparticles onto Liposome Surface for Triggering the Drug Release.  |  Naitlho, N., et al. 2019. AAPS PharmSciTech. 20: 294. PMID: 31432298
  11. Self-assembly and adsorption of cetyltrimethylammonium bromide and didodecyldimethylammonium bromide surfactants at the mica-water interface.  |  Tsagkaropoulou, G., et al. 2019. Soft Matter. 15: 8402-8411. PMID: 31608355
  12. Effective Adsorptive Removal of Methylene Blue from Water by Didodecyldimethylammonium Bromide-Modified Brown Clay.  |  Munir, M., et al. 2020. ACS Omega. 5: 16711-16721. PMID: 32685838
  13. Magnetic Solid-Phase Microextraction Protocol Based on Didodecyldimethylammonium Bromide-Functionalized Nanoparticles for the Quantification of Epirubicin in Biological Matrices.  |  Treder, N., et al. 2023. Pharmaceutics. 15: PMID: 37111712

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Didodecyldimethylammonium bromide, 2 g

sc-239715
2 g
$82.00

Didodecyldimethylammonium bromide, 10 g

sc-239715A
10 g
$255.00