Date published: 2026-8-13

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Dicyclohexyl(4-(N,N-dimethylamino)phenyl)phosphine (CAS 40438-64-0)

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CAS Number:
40438-64-0
Molecular Weight:
317.45
Molecular Formula:
C20H32NP
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dicyclohexyl(4-(N,N-dimethylamino)phenyl)phosphine is a phosphine ligand featuring a dimethylamino group along with two cyclohexyl groups, is generally used as a ligand in reactions catalyzed by transition metals. This compound is a white to pale yellow solid that isn′t highly soluble in water, although it dissolves readily in a variety of organic solvents like dichloromethane, tetrahydrofuran, and acetonitrile. Not only does Dicyclohexyl(4-(N,N-dimethylamino)phenyl)phosphine exhibit antibacterial and antifungal activities, but it also plays a significant role in creating catalysts for organic transformations. Specifically, it′s been employed in various transition metal-catalyzed processes, such as cross-coupling and asymmetric hydrogenation reactions. Additionally, Dicyclohexyl(4-(N,N-dimethylamino)phenyl)phosphine has been utilized as a reagent to synthesize an array of organic compounds, including but not limited to amides, esters, and lactones.


Dicyclohexyl(4-(N,N-dimethylamino)phenyl)phosphine (CAS 40438-64-0) References

  1. Dicyclo-hex-yl[4-(dimethyl-amino)-phen-yl]phosphine selenide.  |  Phasha, ZH., et al. 2012. Acta Crystallogr Sect E Struct Rep Online. 68: o243. PMID: 22259525
  2. Mixture Analysis in Viscous Solvents by NMR Spin Diffusion Spectroscopy: ViscY. Application to High- and Low-Polarity Organic Compounds Dissolved in Sulfolane/Water and Sulfolane/DMSO-d6 Blends.  |  Pedinielli, F., et al. 2020. Anal Chem. 92: 5191-5199. PMID: 32141732
  3. ViscY NMR experiments in phosphoric acid as a viscous solvent for individualization of small molecules within mixtures by spin diffusion.  |  Pedinielli, F., et al. 2021. Analyst. 146: 5316-5325. PMID: 34338684
  4. Ni-catalyzed arylation of alkynes with organoboronic acids and aldehydes to access stereodefined allylic alcohols.  |  Tao, SC., et al. 2023. Chem Sci. 14: 2040-2045. PMID: 36845934

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dicyclohexyl(4-(N,N-dimethylamino)phenyl)phosphine, 250 mg

sc-234612
250 mg
$71.00