Molecular structure of Diclofenac Acyl-β-D-glucuronide, CAS Number: 64118-81-6
Diclofenac Acyl-β-D-glucuronide (CAS 64118-81-6)
Alternate Names:
Diclofenac Acyl-β-D-glucuronide is known as a metabolite of diclofenac.
Application:
Diclofenac Acyl-β-D-glucuronide is a non-steroidal anti-inflammatory compound and COX inhibitor, toxic in vitro.
CAS Number:
64118-81-6
Molecular Weight:
472.27
Molecular Formula:
C20H19Cl2NO8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Diclofenac acyl-β-D-glucuronide is a metabolite of diclofenac, generated through the glucuronidation pathway, which is a major phase II metabolic route for various substances. The compound is utilized in research to study chemical metabolism and to understand the kinetics of diclofenac. Diclofenac acyl-β-D-glucuronide′s role in conjugation reactions is of particular interest, as these reactions increase the water solubility of compounds, facilitating their excretion. By analyzing this metabolite, researchers can gain insights into the enzymes involved in chemical metabolism, such as the family of UDP-glucuronosyltransferases.
Diclofenac Acyl-β-D-glucuronide (CAS 64118-81-6) References
- Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac. | Kenny, JR., et al. 2004. J Med Chem. 47: 2816-25. PMID: 15139759
- Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry. | Osorio, V., et al. 2014. J Chromatogr A. 1347: 63-71. PMID: 24835592
- Involvement of Reactive Metabolites of Diclofenac in Cytotoxicity in Sandwich-Cultured Rat Hepatocytes. | Kawase, A., et al. 2017. Int J Toxicol. 36: 260-267. PMID: 28553770
Inhibitor of:
Cox.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Diclofenac Acyl-β-D-glucuronide, 1 mg | sc-207559 | 1 mg | $455.00 | |||
Diclofenac Acyl-β-D-glucuronide, 2 mg | sc-207559A | 2 mg | $746.00 | |||
Diclofenac Acyl-β-D-glucuronide, 5 mg | sc-207559B | 5 mg | $1785.00 | |||
Diclofenac Acyl-β-D-glucuronide, 10 mg | sc-207559C | 10 mg | $2715.00 |