Date published: 2026-5-6

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Dichloromethyl methyl ether (CAS 4885-02-3)

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Alternate Names:
α,α-Dichloromethyl methyl ether; 1,1-Dichlorodimethyl ether
Application:
Dichloromethyl methyl ether is a common formylating reagent for aromatic compounds
CAS Number:
4885-02-3
Purity:
≥97%
Molecular Weight:
114.96
Molecular Formula:
C2H4Cl2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dichloromethyl methyl ether is a common formylating reagent for aromatic compounds, chlorinating agent for carboxylic acids. It also reacts with borinic esters for the preparation of alkenones. Used as an intermediate for the synthesis of trifluoroacetic acid from hydrochloric acid and methanol.


Dichloromethyl methyl ether (CAS 4885-02-3) References

  1. A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate.  |  Ohsawa, K., et al. 2013. J Org Chem. 78: 3438-44. PMID: 23477294
  2. Formylation of electron-rich aromatic rings mediated by dichloromethyl methyl ether and TiCl4: scope and limitations.  |  Ramos-Tomillero, I., et al. 2015. Molecules. 20: 5409-22. PMID: 25822080
  3. Alternative syntheses and related n.m.r. studies of precursors for internal beta-D-galactopyranosyl residues in oligosaccharides, allowing chain extension at O-4.  |  Kovác, P. and Taylor, RB. 1987. Carbohydr Res. 167: 153-73. PMID: 3690568
  4. Di- and tri-saccharide glycosyl donors for the synthesis of fragments of the O-specific antigen of Shigella dysenteriae type 1.  |  Kovác, P. 1993. Carbohydr Res. 245: 219-31. PMID: 7690306
  5. Synthesis of the methyl alpha-glycosides of a di-, tri-, and a tetra-saccharide fragment mimicking the terminus of the O-polysaccharide of Vibrio cholerae O:1, serotype Ogawa.  |  Lei, P., et al. 1996. Carbohydr Res. 281: 47-60. PMID: 8839176

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dichloromethyl methyl ether, 25 g

sc-252701
25 g
$46.00