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Dibutyl sebacate (CAS 109-43-3)

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Alternate Names:
Decanedioic acid dibutyl ester; Sebacic acid dibutyl ester
CAS Number:
109-43-3
Molecular Weight:
314.46
Molecular Formula:
C18H34O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dibutyl sebacate, an ester of sebacic acid and butanol, has emerged as a valuable compound in scientific research, particularly in the fields of polymer chemistry and materials science. Its mechanism of action primarily revolves around its role as a plasticizer, wherein it improves the flexibility, durability, and processability of polymers. Researchers have extensively studied its interaction with polymer matrices, elucidating its ability to decrease the glass transition temperature and increase the elongation at break of various polymers, including polyvinyl chloride (PVC), polyethylene (PE), and polyvinyl acetate (PVAc). Furthermore, dibutyl sebacate has been employed as a key component in the formulation of adhesives, coatings, and films, enhancing their mechanical properties and adhesion to substrates. Its compatibility with a wide range of polymers and its low volatility make it an ideal candidate for applications requiring long-term stability and performance. Moreover, dibutyl sebacate has found utility in biomedical research as a component in biodegradable polymers for drug delivery systems and tissue engineering scaffolds, owing to its biocompatibility and controlled release properties. Overall, dibutyl sebacate represents a versatile chemical tool in research endeavors spanning polymer science, materials engineering, and biomedical applications, offering opportunities for innovation and advancement in various scientific disciplines.


Dibutyl sebacate (CAS 109-43-3) References

  1. Toxicity of butyl stearate, dibutyl sebacate, dibutyl phthalate, and methoxyethyl oleate.  |  SMITH, CC. 1953. AMA Arch Ind Hyg Occup Med. 7: 310-8. PMID: 13039587
  2. In situ forming implants for periodontitis treatment with improved adhesive properties.  |  Do, MP., et al. 2014. Eur J Pharm Biopharm. 88: 342-50. PMID: 24833006
  3. Effect of substitution of plasticizer dibutyl phthalate with dibutyl sebacate on Eudragit® RS30D drug release rate control.  |  Chaudhary, RS., et al. 2019. Pharm Dev Technol. 24: 276-282. PMID: 29688126
  4. The Influence of Plasticizers on the Response Characteristics of the Surfactant Sensor for Cationic Surfactant Determination in Disinfectants and Antiseptics.  |  Sakač, N., et al. 2021. Sensors (Basel). 21: PMID: 34069524
  5. The effect of plastic additives on Shewanella oneidensis growth and function.  |  Fawcett, LP., et al. 2021. Environ Sci Process Impacts. 23: 956-966. PMID: 34085083
  6. Effect of plasticizers on drug-in-adhesive patches containing 5-fluorouracil.  |  Kim, S., et al. 2022. Int J Pharm. 611: 121316. PMID: 34838623
  7. Drug-plasticizer interactions causing solid state transitions of rifaximin.  |  Höfler, K., et al. 2022. Int J Pharm. 625: 122128. PMID: 35995318
  8. Thermomechanical Properties of Nontoxic Plasticizers for Polyvinyl Chloride Predicted from Molecular Dynamics Simulations.  |  Jagarlapudi, SS., et al. 2023. ACS Appl Mater Interfaces. 15: 24858-24867. PMID: 37167600
  9. Differences in body wall metabolites of Apostichopus japonicus of different ages in liquid chromatography-tandem mass spectrometry.  |  Yang, X., et al. 2023. Comp Biochem Physiol Part D Genomics Proteomics. 47: 101109. PMID: 37451048
  10. Development and optimization of film forming non-pressurized liquid bandage for wound healing by Box-Behnken statistical design.  |  Saifullah, Q., et al. 2023. Saudi Pharm J. 31: 101864. PMID: 38028211
  11. Acetyl tributyl citrate and dibutyl sebacate inhibit the growth of cultured mammalian cells.  |  Mochida, K., et al. 1996. Bull Environ Contam Toxicol. 56: 635-7. PMID: 8645922

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dibutyl sebacate, 250 ml

sc-214876
250 ml
$40.00

Dibutyl sebacate, 1 L

sc-214876A
1 L
$99.00