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Dibromochloromethane (CAS 124-48-1)

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Alternate Names:
Chlorodibromomethane
CAS Number:
124-48-1
Molecular Weight:
208.28
Molecular Formula:
Br2CHCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dibromochloromethane is a colorless liquid used in studies due to its attributes such as water solubility, non-combustibility, and minimal toxicity. It is soluble in water, ether, and ethanol, and is non-flammable. TThe chemical properties of Dibromochloromethane include its reactivity with nucleophiles, such as water and alcohols, to form dihalomethylalcohols. It can partake in halogen exchange interactions with different halomethanes, which yields new halomethane compounds. Dibromochloromethane serves multiple purposes in scientific research, for instance, being used as a purifying agent in water purification facilities and pools, acting as a solvent during organic synthesis, and functioning as a reagent in analytical chemistry endeavors. Affords bromochlorocarbene under phase-transfer conditions.


Dibromochloromethane (CAS 124-48-1) References

  1. Chlorodibromomethane.  |  . 1999. IARC Monogr Eval Carcinog Risks Hum. 71 Pt 3: 1331-8. PMID: 10476407
  2. Risk assessment case study--chloroform and related substances.  |  Fawell, J. 2000. Food Chem Toxicol. 38: S91-5. PMID: 10717377
  3. Toxicities of microencapsulated tribromomethane, dibromochloromethane and bromodichloromethane administered in the diet to Wistar rats for one month.  |  Aida, Y., et al. 1992. J Toxicol Sci. 17: 119-33. PMID: 1453497
  4. Ninety-day oral toxicity study of dibromochloromethane in Sprague-Dawley rats.  |  Daniel, FB., et al. 1990. Drug Chem Toxicol. 13: 135-54. PMID: 2276338
  5. Exposure to disinfectant by-products and the risk of stillbirth in Massachusetts.  |  Rivera-Núñez, Z., et al. 2018. Occup Environ Med. 75: 742-751. PMID: 30061312
  6. Toxicological aspects of trihalomethanes: a systematic review.  |  de Castro Medeiros, L., et al. 2019. Environ Sci Pollut Res Int. 26: 5316-5332. PMID: 30607849
  7. Use of multiple regression models for predicting the formation of bromoform and dibromochloromethane during ballast water treatment based on an advanced oxidation process.  |  Zhang, X., et al. 2019. Environ Pollut. 254: 113028. PMID: 31421575
  8. Bromoform, dibromochloromethane, and dibromomethane over the East China Sea and the western Pacific Ocean: Oceanic emission and spatial variation.  |  Liu, SS., et al. 2020. Chemosphere. 257: 127151. PMID: 32470539
  9. Trihalomethanes in Water Supply System and Water Distribution Networks.  |  Sriboonnak, S., et al. 2021. Int J Environ Res Public Health. 18: PMID: 34501655
  10. Relationship between Blood Trihalomethane Concentrations and Serum Thyroid Function Measures in U.S. Adults.  |  Sun, Y., et al. 2021. Environ Sci Technol. 55: 14087-14094. PMID: 34617747
  11. Ambient volatile organic compounds in tropical environments: Potential sources, composition and impacts - A review.  |  Mohd Hanif, N., et al. 2021. Chemosphere. 285: 131355. PMID: 34710962
  12. Multi-exposure human health risks assessment of trihalomethanes in drinking water of Egypt.  |  Mishaqa, EI., et al. 2022. Environ Res. 207: 112643. PMID: 34973941
  13. Comparative renal and hepatotoxicity of halomethanes: bromodichloromethane, bromoform, chloroform, dibromochloromethane and methylene chloride.  |  Condie, LW., et al. 1983. Drug Chem Toxicol. 6: 563-78. PMID: 6653442
  14. Toxicology of organic drinking water contaminants: trichloromethane, bromodichloromethane, dibromochloromethane and tribromomethane.  |  Munson, AE., et al. 1982. Environ Health Perspect. 46: 117-26. PMID: 7151752

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dibromochloromethane, 5 g

sc-239686
5 g
$41.00

Dibromochloromethane, 10 g

sc-239686A
10 g
$67.00