Molecular structure of Dibenzoylmethane, CAS Number: 120-46-7
Dibenzoylmethane (CAS 120-46-7)
Alternate Names:
1,3-Diphenyl-1,3-propanedione
Application:
Dibenzoylmethane is a compound known to inhibit tumorigenesis in mice
CAS Number:
120-46-7
Molecular Weight:
224.25
Molecular Formula:
C15H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Technical Information
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SDS & Certificate of Analysis
Dibenzoylmethane functions as a UV filter in experimental applications. It operates by absorbing and dissipating UV radiation, thereby preventing damage to the molecules in the system under study. At the molecular level, dibenzoylmethane interacts with UV radiation, causing a change in its energy state and preventing it from causing photochemical reactions in the experimental environment. Dibenzoylmethane′s mechanism of action involves its ability to absorb UV radiation and convert it into less harmful forms of energy, thereby protecting the molecules or materials being studied from potential damage. In this way, dibenzoylmethane plays a functional role in shielding the experimental system from the harmful effects of UV radiation.
Dibenzoylmethane (CAS 120-46-7) References
- Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice. | Lin, CC., et al. 2001. Cancer Lett. 168: 125-32. PMID: 11403916
- Butyl methoxy dibenzoylmethane. | Kockler, J., et al. 2013. Profiles Drug Subst Excip Relat Methodol. 38: 87-111. PMID: 23668403
- Dibenzoylmethane, hydroxydibenzoylmethane and hydroxymethyldibenzoylmethane inhibit phorbol-12-myristate 13-acetate‑induced breast carcinoma cell invasion. | Liao, YF., et al. 2015. Mol Med Rep. 11: 4597-604. PMID: 25650742
- A dibenzoylmethane derivative inhibits lipopolysaccharide-induced NO production in mouse microglial cell line BV-2. | Takano, K., et al. 2018. Neurochem Int. 119: 126-131. PMID: 28390951
- Boron difluoride dibenzoylmethane derivatives: Electronic structure and luminescence. | Tikhonov, SA., et al. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 189: 563-570. PMID: 28866412
- White light color tuning ability of hybrid Dibenzoylmethane/YAG:Ce nanophosphor. | Rashmi,. and Dwivedi, Y. 2019. Spectrochim Acta A Mol Biomol Spectrosc. 206: 141-146. PMID: 30098480
- Dibenzoylmethane ameliorates lipid-induced inflammation and oxidative injury in diabetic nephropathy. | Lee, ES., et al. 2019. J Endocrinol. 240: 169-179. PMID: 30475214
- Characterization and Systemic Delivery of Dibenzoylmethane via the Intranasal Route. | Vora, D., et al. 2021. AAPS PharmSciTech. 22: 30. PMID: 33404926
- Investigations on the Photochemical Reaction Mechanisms of Selected Dibenzoylmethane Compounds. | Wang, J., et al. 2021. J Org Chem. 86: 7594-7602. PMID: 34013727
- Dibenzoylmethane derivative inhibits melanoma cancer in vitro and in vivo through induction of intrinsic and extrinsic apoptotic pathways. | Nascimento, FR., et al. 2022. Chem Biol Interact. 351: 109734. PMID: 34742685
- Voltammetric and Fluorimetric Studies of Dibenzoylmethane on Glassy Carbon Electrodes and Its Interaction with Tetrakis (3,5-Dicarboxyphenoxy) Cavitand Derivative. | Kiss, L., et al. 2022. Molecules. 28: PMID: 36615382
- Dibenzoylmethane ameliorates adiposity-mediated neuroinflammatory response and inflammation-mediated neuronal cell death in mouse microglia and neuronal cells. | You, YL. and Choi, HS. 2023. Food Sci Biotechnol. 32: 1123-1132. PMID: 37215256
- Effect of dietary curcumin and dibenzoylmethane on formation of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice. | Huang, MT., et al. 1998. Carcinogenesis. 19: 1697-700. PMID: 9771944
Inhibitor of:
HRI, and Olfr605.Activator of:
CT45-3, CYP1B1, FACL6, and SIAH-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dibenzoylmethane, 25 g | sc-204719 | 25 g | $37.00 | |||
Dibenzoylmethane, 100 g | sc-204719A | 100 g | $51.00 |