Date published: 2025-10-30

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Dibenzocyclooctyne-N-hydroxysuccinimidyl ester (CAS 1353016-71-3)

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Alternate Names:
DBCO-NHS ester; DBCO-SE
Application:
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester is an amine reactive crosslinker for incorporation of the cyclooctyne moiety
CAS Number:
1353016-71-3
Molecular Weight:
402.40
Molecular Formula:
C23H18N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dibenzocyclooctyne-N-hydroxysuccinimidyl ester, also know as DBCO-NHS ester is a succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. It can be used in applications such as: protein-peptide conjugates, antibody-enzyme or antibody-drug conjugates, protein or peptide-oligonucleotide conjugates and surface modification.


Dibenzocyclooctyne-N-hydroxysuccinimidyl ester (CAS 1353016-71-3) References

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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dibenzocyclooctyne-N-hydroxysuccinimidyl ester, 1 mg

sc-397268
1 mg
$26.00

Dibenzocyclooctyne-N-hydroxysuccinimidyl ester, 5 mg

sc-397268A
5 mg
$79.00