Date published: 2025-12-8

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Dibenzo-18-crown-6 (CAS 14187-32-7)

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Alternate Names:
2,5,8,15,18,21-hexaoxatricyclo[20.4.0.09,14]hexacosa-1(26),9,11,13,22,24-hexaene
CAS Number:
14187-32-7
Molecular Weight:
360.40
Molecular Formula:
C20H24O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dibenzo-18-crown-6 presents as a colorless, crystalline solid, insoluble in water but soluble in organic solvents. Comprising two benzene rings linked by a crown ether bridge, it forms a cyclic polyether structure. Researchers have employed Dibenzo-18-crown-6 in a range of scientific applications, including synthesis, chromatography, and spectroscopy, capitalizing on its ability to create robust complexes with metal ions. Its deployment as a ligand in coordination chemistry has facilitated the formation of potent complexes with metal ions. This, in turn, has facilitated the examination of metal complex properties and their potential applications. Additionally, it has served as a component in the synthesis of other organic compounds like crown ethers and cyclic polyethers. Dibenzo-18-crown-6 has been instrumental in studying the interplay between metal ions and organic molecules, as well as exploring the structure and properties of metal complexes. The mechanism of action of Dibenzo-18-crown-6 hinges on its ability to establish robust complexes with metal ions. Its structure encompasses two benzene rings connected by a crown ether bridge. This bridge comprises a ring structure of six oxygen atoms capable of binding to metal ions. The interaction between the metal ion and the crown ether bridge is bolstered by hydrogen bonds, electrostatic interactions, and van der Waals forces. Such strong binding affords the formation of stable complexes between the metal ion and Dibenzo-18-crown-6, facilitating their application across diverse scientific endeavors.


Dibenzo-18-crown-6 (CAS 14187-32-7) References

  1. Laser spectroscopic study on the conformations and the hydrated structures of benzo-18-crown-6-ether and dibenzo-18-crown-6-ether in supersonic jets.  |  Kusaka, R., et al. 2007. Phys Chem Chem Phys. 9: 4452-9. PMID: 17690770
  2. Conformational polymorph of o-aminoanilinium(dibenzo[18]crown-6) supramolecules in [Ni(dmit)2]- salts.  |  Akutagawa, T., et al. 2010. Chem Asian J. 5: 520-9. PMID: 20029890
  3. 18-Crown-6 and dibenzo-18-crown-6 assisted extraction of cesium from water into room temperature ionic liquids and its correlation with stability constants for cesium complexes.  |  Vendilo, AG., et al. 2009. Molecules. 14: 5001-16. PMID: 20032873
  4. 4-Methoxyanilinium tetrafluoroborate-dibenzo-18-crown-6 (1/1).  |  Fu, XQ., et al. 2010. Acta Crystallogr C. 66: o433-5. PMID: 20679724
  5. Dibenzo-18-crown-6.  |  de Lima, GM., et al. 2008. Acta Crystallogr Sect E Struct Rep Online. 64: o2001. PMID: 21201199
  6. Supramolecular cations of the m-fluoroanilinium(dibenzo[18]crown-6) in ferromagnetic salt.  |  Endo, T., et al. 2011. Dalton Trans. 40: 1491-6. PMID: 21243157
  7. Hydro-nium perchlorate-dibenzo-18-crown-6 (1/1): monoclinic polymorph.  |  Pojarová, M., et al. 2010. Acta Crystallogr Sect E Struct Rep Online. 66: o3341-2. PMID: 21589614
  8. Theobrominium perchlorate dibenzo-18-crown-6 3.25-hydrate.  |  Kulikov, V. and Meyer, G. 2013. Acta Crystallogr Sect E Struct Rep Online. 69: o1027. PMID: 24046607
  9. Vibrational analysis of dibenzo-18-crown-6. Effect of dispersion correction on the calculated vibrational spectra.  |  Al-Jallal, NA. and El-Azhary, AA. 2017. Spectrochim Acta A Mol Biomol Spectrosc. 184: 23-29. PMID: 28477513
  10. Conformational Study of the Structure of dibenzo-18-crown-6. Comparison with 18-crown-6.  |  Al-Jallal, NA. and El-Azhary, AA. 2017. J Mol Graph Model. 75: 49-54. PMID: 28505566
  11. Highly selective enrichment of phosphopeptides using poly(dibenzo-18-crown-6) as a solid-phase extraction material.  |  Mirza, MR., et al. 2019. Biomed Chromatogr. 33: e4567. PMID: 31042298
  12. Geometric and Electronic Structures of Ag+(benzo-18-crown-6), Ag+(dibenzo-18-crown-6), and Ag+(dibenzo-15-crown-5) Complexes Investigated by Cold Gas-Phase Spectroscopy.  |  Kitamura, Y., et al. 2019. J Phys Chem A. 123: 9185-9192. PMID: 31545041
  13. Investigation of Dendrimer Transfer Behaviors at the Micro-Water/1,2-Dichloroethane Interface Facilitated by Dibenzo-18-Crown-6.  |  Li, M., et al. 2021. Anal Chem. 93: 1515-1522. PMID: 33356146
  14. Dibenzo-18-crown-6-based carbon paste sensors for the nanomolar potentiometric determination of daclatasvir dihydrochloride: An anti-HCV drug and a potential candidate for treatment of SARS-CoV-2.  |  Ahmed, YM., et al. 2022. Microchem J. 177: 107276. PMID: 35169329

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dibenzo-18-crown-6, 2.5 g

sc-252682
2.5 g
$27.00

Dibenzo-18-crown-6, 10 g

sc-252682A
10 g
$60.00