Date published: 2026-5-20

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Diamino Biotin (CAS 22342-46-7)

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Alternate Names:
(2S,3S,4R)-3,4-Diaminotetrahydro-2-thiophenepentanoic Acid
Application:
Diamino Biotin is a biotin impurity
CAS Number:
22342-46-7
Molecular Weight:
218.32
Molecular Formula:
C9H18N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diamino biotin is a biotin analog that is used in biochemical and molecular biology research for its ability to bind strongly to proteins, such as avidin and streptavidin. This binding property is harnessed in a variety of assay methods, including the labeling and detection of proteins, nucleic acids, and other biomolecules. Its additional amino groups allow for further conjugation with other molecules, which enhances its utility as a versatile tag in affinity chromatography and the purification of biomolecules. In the field of proteomics, diamino biotin is used to investigate post-translational modifications and protein interactions. It is also a component in the development of biosensors, whereby it is attached to surfaces or electrodes to capture specific biomolecules for detection and quantification.


Diamino Biotin (CAS 22342-46-7) References

  1. Preincubation of recombinant Ipa proteins of Shigella sonnei promotes entry of non-invasive Escherichia coli into HeLa cells.  |  Terajima, J., et al. 1999. Microb Pathog. 27: 223-30. PMID: 10502463
  2. Expression vectors for studying cytoskeletal proteins in Dictyostelium discoideum.  |  Knetsch, ML., et al. 2002. J Muscle Res Cell Motil. 23: 605-11. PMID: 12952059
  3. Imaging Biotin Trafficking In Vivo with Positron Emission Tomography.  |  Bongarzone, S., et al. 2020. J Med Chem. 63: 8265-8275. PMID: 32658479
  4. Purification and characterization of recombinant affinity peptide-tagged oat phytochrome A.  |  Murphy, JT. and Lagarias, JC. 1997. Photochem Photobiol. 65: 750-8. PMID: 9114754

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diamino Biotin, 25 mg

sc-391399C
25 mg
$223.00

Diamino Biotin, 50 mg

sc-391399D
50 mg
$286.00

Diamino Biotin, 100 mg

sc-391399
100 mg
$379.00

Diamino Biotin, 250 mg

sc-391399A
250 mg
$775.00

Diamino Biotin, 500 mg

sc-391399B
500 mg
$1441.00

Diamino Biotin, 1 g

sc-391399E
1 g
$2388.00