Molecular structure of Di-n-hexyl phthalate, CAS Number: 84-75-3
Di-n-hexyl phthalate (CAS 84-75-3)
Alternate Names:
Dihexyl Phthalate; Phthalic Acid Dihexyl Ester
CAS Number:
84-75-3
Purity:
≥97%
Molecular Weight:
334.45
Molecular Formula:
C20H30O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Di-n-hexyl phthalate (DHP) is an organic compound with low volatility. It is a plasticizer, which is a substance added to plastics to increase their flexibility, durability, and longevity. It is in the manufacture of polyvinyl chloride (PVC), polyethylene terephthalate (PET), and polystyrene (PS) plastics. Di-n-hexyl phthalate can interact with cell membranes and disrupt their normal functioning, as well as cause DNA damage in cells. It also interferes with the metabolism of certain hormones, such as testosterone, which can lead to reproductive and developmental toxicity.
Di-n-hexyl phthalate (CAS 84-75-3) References
- Effects on male rats of di-(2-ethylhexyl) phthalate and di-n-hexylphthalate administered alone or in combination. | Howarth, JA., et al. 2001. Toxicol Lett. 121: 35-43. PMID: 11312035
- NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Di-n-Hexyl Phthalate (DnHP). | ,. 2003. NTP CERHR MON. i-III90. PMID: 15995729
- Toxicity of seven phthalate esters to embryonic development of the abalone Haliotis diversicolor supertexta. | Liu, Y., et al. 2009. Ecotoxicology. 18: 293-303. PMID: 19030987
- Differential developmental toxicities of di-n-hexyl phthalate and dicyclohexyl phthalate administered orally to rats. | Saillenfait, AM., et al. 2009. J Appl Toxicol. 29: 510-21. PMID: 19391110
- Effects of in utero exposure to di-n-hexyl phthalate on the reproductive development of the male rat. | Saillenfait, AM., et al. 2009. Reprod Toxicol. 28: 468-76. PMID: 19577633
- In utero exposure to dicyclohexyl and di-n-hexyl phthalate possess genotoxic effects on testicular cells of male rats after birth in the comet and TUNEL assays. | Ahbab, MA., et al. 2014. Hum Exp Toxicol. 33: 230-9. PMID: 23836838
- Influence of in utero di-n-hexyl phthalate and dicyclohexyl phthalate on fetal testicular development in rats. | Aydoğan Ahbab, M. and Barlas, N. 2015. Toxicol Lett. 233: 125-37. PMID: 25637754
- Evaluation of the effects of deltamethrin on the fetal rat testis. | Saillenfait, AM., et al. 2016. J Appl Toxicol. 36: 1505-15. PMID: 26934186
- Analytical method for urinary metabolites as biomarkers for monitoring exposure to phthalates by gas chromatography/mass spectrometry. | Yoshida, T. 2017. Biomed Chromatogr. 31: PMID: 27925246
- Comparative developmental toxicity evaluation of di- n-hexyl phthalate and dicyclohexyl phthalate in rats. | Ahbab, MA., et al. 2017. Toxicol Ind Health. 33: 696-716. PMID: 28854868
- Influence of in utero di-n-hexyl phthalate and di-cyclohexyl phthalate exposure on the endocrine glands and T3, T4, and TSH hormone levels of male and female rats: Postnatal outcomes. | Barlas, N., et al. 2020. Toxicol Ind Health. 36: 399-416. PMID: 32602421
- Di-n-hexyl phthalate causes Leydig cell hyperplasia in rats during puberty. | Ye, J., et al. 2020. Toxicol Lett. 332: 213-221. PMID: 32693021
- Phthalate Esters Released from Plastics Promote Biofilm Formation and Chlorine Resistance. | Wang, H., et al. 2022. Environ Sci Technol. 56: 1081-1090. PMID: 34991317
- Effects of the in-utero dicyclohexyl phthalate and di-n-hexyl phthalate administration on the oxidative stress-induced histopathological changes in the rat liver tissue correlated with serum biochemistry and hematological parameters. | Aydemir, D., et al. 2023. Front Endocrinol (Lausanne). 14: 1128202. PMID: 37274322
- Comparison of the short-term effects of di(2-ethylhexyl) phthalate, di(n-hexyl) phthalate, and di(n-octyl) phthalate in rats. | Mann, AH., et al. 1985. Toxicol Appl Pharmacol. 77: 116-32. PMID: 3966235
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Di-n-hexyl phthalate, 10 g | sc-278933 | 10 g | $96.00 | |||
Di-n-hexyl phthalate, 50 g | sc-278933A | 50 g | $333.00 |